Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

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Personalised medicine in oncology: A new study helps predict the risk of serious side effects from chemotherapy

PublicationResearch Published on 25. 07. 2025 Reading time: 2 minutes

Kymolyzer: A tool for automatic analysis of time-lapse microscopic data

Research Published on 24. 07. 2025 Reading time: 1 minute

From stars to DNA: Toxicologist Kateřina Hoňková will be a guest at a panel discussion at the famous festival Colours of Ostrava

InvitationPopularisation of Science Published on 17. 07. 2025 Reading time: 2 minutes

New models for fighting pancreatic cancer: How science is testing breakthrough therapies

PublicationResearch Published on 15. 07. 2025 Reading time: 3 minutes

Quality control of NMDA receptors: the influence of the ligand-binding domain

PublicationResearch Published on 09. 07. 2025 Reading time: 3 minutes

Nanoparticles and stem cells: A new direction in the treatment of damaged corneas

PublicationResearch Published on 25. 06. 2025 Reading time: 2 minutes
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Events

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02. 09. 2025 - 11. 09. 2025

NanoEnviCz: Summer School for Nanomaterials 2025

Professional EventsWorkshop

04. 09. 2025

Institutional Seminar Series 9/2025

Professional EventsSeminar

02. 10. 2025

Institutional Seminar Series 10/2025

Institutional SeminarProfessional Events

06. 11. 2025

Institutional Seminar Series 11/2025

Professional EventsSeminar

12. 11. 2025 - 14. 11. 2025

Introduction to Programming for Image Processing

CourseCzech-BioimagingMicroscopy

04. 12. 2025

Institutional Seminar Series 12/2025

Professional EventsSeminar
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2023 – 2024 (pdf, 28616 kB)
  • 1975 Established
  • 219 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

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Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

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Latest Publications

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Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer

 Department of Molecular Biology of Cancer AutořiSimoes A. R.Carlés González S.Lopez-Doldan M. C.Duran G.Fernández-Montes A.Fernandez M. P.Salgado Fernandez M.Garcia Mata J.Paez D.Riera P.Guino E.Lopez-Fernandez L.Garcia de Santiago B.López Aspiroz E.Rojas A.Castells A.Castellvi-Bel S.Ruiz Ponte C.Vymetálková V.Carracedo A.Fernandez-Rozadilla C. Published on 2025 Metadata Br J Pharmacol . 2025 Jul 7. doi: 10.1111/bph.70051. Online ahead of print.

Biomimetic Tumour Model Systems for Pancreatic Ductal Adenocarcinoma in Relation to Photodynamic Therapy

 Department of Molecular Biology of Cancer AutořiSmith O. M.Lintern N.Tian J.Mesquita B. M.Oliveira S.Vymetálková V.Prakash J.Smith A. M.Jayne D. G.Heger M.Khaled Y. S.Photodynamic Therapy Study Group Published on 2025 Metadata Int J Mol Sci . 2025 Jul 2;26(13):6388. doi: 10.3390/ijms26136388.

Distinct Regulation of Early Trafficking of the NMDA Receptors by the Ligand-Binding Domains of the GluN1 and GluN2A Subunits

 Department of Neurochemistry AutořiNetolický J.Baráčková P.Misiachna A.Kolcheva M.Řeháková K.Hemelíková K.Kortus S.Langore E.Doderović J.Ladislav M.Korabecny J.Otyepka M.Srejber M.Horák M. Published on 2025 Metadata J Neurosci . 2025 Jun 25;45(26):e0226242025. doi: 10.1523/JNEUROSCI.0226-24.2025.

Combined Therapy Using Mesenchymal Stem Cells and Metal Nanoparticles: Perspectives for Ocular Injuries and Diseases

 Department of Toxicology and Molecular Epidemiology AutořiHoláň V.Javorková E.Heřmánková B.Rössner P. Published on 2025 Metadata Int J Nanomedicine . 2025 Jun 12:20:7403-7414. doi: 10.2147/IJN.S527928. eCollection 2025.

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

 Department of Neuroregeneration AutořiSmejkalová B.Ornaghi M.Štěpánková K.Schiweck J.Urdzíková-Machová L.Huelse R.Mueller S.Boehm-Sturm P.Kwok J. C. F.Fawcett J.Murk K.Eickholt B. J.Jendelová P. Published on 2025 Metadata Glia . 2025 Jun 11. doi: 10.1002/glia.70048. Online ahead of print.

Electrospun Poly(L-lactide-co-ε-caprolactone) Nanofibers with Hydroxyapatite Nanoparticles Mimic Cellular Interplay in Bone Regeneration

 Department of Tissue Engineering AutořiŠebová E.Leal F.Rampichová M.Nirwan V. P.Fahmi A.Costa P. F.Filová E. Published on 2025 Metadata Int J Mol Sci . 2025 Jun 4;26(11):5383. doi: 10.3390/ijms26115383.

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

 Department of Molecular Biology of Cancer AutořiPiccinno G.Thompson K. N.Manghi P.Ghazi A. R.Thomas A. M.Blanco-Míguez A.Asnicar F.Mladenovic K.Pinto F.Armanini F....Vymetálková V....Vodička P....Pardini B.Cordero F.Song M.Chan A. T.Derosa L.Zitvogel L.Huttenhower C.Naccarati A.Budinska E.Segata N. Published on 2025 Metadata Nat Med . 2025 Jun 3. doi: 10.1038/s41591-025-03693-9. Online ahead of print.

Neuroprotective Riluzole-Releasing Electrospun Implants for Spinal Cord Injury

 Department of Tissue Engineering AutořiUllrich M. M.Pulipaka B.Yin J.Hlinková J.Zhang F.Chan M. W.O'Brien F. J.Dervan A.Dziemidowicz K. Published on 2025 Metadata Mol Pharm . 2025 Jun 2;22(6):2905-2916. doi: 10.1021/acs.molpharmaceut.4c01270. Epub 2025 May 16.

Single-Atom Colloidal Nanorobotics Enhanced Stem Cell Therapy for Corneal Injury Repair

 Department of Toxicology and Molecular Epidemiology AutořiJu X.Javorková E.Michalička J.Pumera M. Published on 2025 Metadata ACS Nano. 2025 May 27;19(20):19095-19115. doi: 10.1021/acsnano.4c18874. Epub 2025 May 13.
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