Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

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News

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Open positions at the IEM CAS

Open Position Published on 26. 09. 2023 Reading time: 1 minute

IEM CAS is a part of the NanoShiled research project

Project Published on 25. 09. 2023 Reading time: 1 minute

Scientists of the IEM CAS are co-authors of a new expert statement of the Czech Academy of Sciences

OtherPopularisation of Science Published on 01. 09. 2023 Reading time: 2 minutes
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Events

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05. 10. 2023

Institutional Seminar Series 10/2023

Institutional SeminarProfessional Events

02. 11. 2023

Institutional Seminar Series 11/2023

Institutional SeminarProfessional Events

06. 11. 2023 - 12. 11. 2023

Week of the Czech Academy of Sciences

Popularisation of Science

23. 11. 2023 - 24. 11. 2023

Mini-Symposium BIOCEV Regeneration III.

Symposium

07. 12. 2023

Institutional Seminar Series 12/2023

Institutional SeminarProfessional Events
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Czech-Bioimaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2021-2022 (pdf, 46372 kB)
  • 1975 Established
  • 202 Employees
  • 74 Projects
  • 90 Publications (2022)

Research Departments and Centres

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Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Nanotoxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of the Molecular Biology of Cancer

Research Department

Head of the Department

Pavel Vodička

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Genetic Toxicology and Epigenetics

Research Department

Head of the Department

Jan Topinka

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Latest Publications

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Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment

 DepartmentDepartment of Genetic Toxicology and Epigenetics AutořiMussalo L.Avesani S.Shahbaz M. A.Závodná T.Saveleva L.Järvinen A.Lampinen R.Belaya I.Krejčík Z.Ivanova M.Hakkarainen H.Kalapudas J.Penttilä E.Löppönen H.Koivisto A. M.Malm T.Topinka J.Giugno R.Aakko-Saksa P.Chew S.Rönkkö T.Jalava P.Kanninen K. M. Published on 2023 Metadata Sci Total Environ . 2023 Sep 13;905:167038. doi: 10.1016/j.scitotenv.2023.167038. Online ahead of print.

Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin-9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior

 DepartmentDepartment of Genetic Toxicology and Epigenetics AutořiMüllerová M.Hovorková M.Závodná T.Červenková Štastná L.Krupková A.Hamala V.Nováková K.Topinka J.Bojarová P.Strašák T. Published on 2023 Metadata Biomacromolecules . 2023 Sep 8. doi: 10.1021/acs.biomac.3c00426. Online ahead of print.

A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk

 DepartmentDepartment of the Molecular Biology of Cancer AutořiAglago E. K.Kim A. E.Lin Y.Qu C.Evangelou M.Ren Y.Morrison J.Albanes D.Arndt V.Barry E. L.Baurley J. W.Berndt S. I.Bien S. A.Bishop D. T.Bouras E.Brenner H.Buchanan D. D.Budiarto A.Carreras-Torres R.Casey G.Cenggoro T. W.Chan A. T.Chang-Claude J.Chen X.Conti D. V.Devall M.Díez-Obrero V.Dimou N.Drew D.Figueiredo J. C.Gallinger S.Giles G. G.Gruber S. B.Gsur A.Gunter M. J.Hampel H.Harlid S.Hidaka A.Harrison T. A.Hoffmeister M.Huyghe J. R.Jenkins M. A.Jordahl K.Joshi A. D.Kawaguchi E. S.Keku T. O.Kundaje A.Larsson S. C.Le Marchand L.Lewinger J. P.Li L.Lynch B. M.Mahesworo B.Mandic M.Obón-Santacana M.Moreno V.Murphy N.Nan H.Nassir R.Newcomb P. A.Ogino S.Ose J.Pai R. K.Palmer J. R.Papadimitriou N.Pardamean B.Peoples A. R.Platz E. A.Potter J. D.Prentice R. L.Rennert G.Ruiz-Narvaez E.Sakoda L. C.Scacheri P. C.Schmit S. L.Schoen R. E.Shcherbina A.Slattery M. L.Stern M. C.Su Y. R.Tangen C. M.Thibodeau S. N.Thomas D. C.Tian Y.Ulrich C. M.van Duijnhoven F. J. B.Van Guelpen B.Visvanathan K.Vodička P.Wang J.White E.Wolk A.Woods M. O.Wu A. H.Zemlianskaia N.Hsu L.Gauderman W. J.Peters U.Tsilidis K. K.Campbell P. T. Published on 2023 Metadata Cancer Res . 2023 May 30;CAN-22-3713. doi: 10.1158/0008-5472.CAN-22-3713. Online ahead of print.

A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study

 DepartmentDepartment of the Molecular Biology of Cancer AutořiPardini B. Ferrero G.Tarallo S.Gallo G.Francavilla A.Licheri N.Trompetto M.Clerico G.Senore C.Peyre S.Vymetálková V.Vodičková L.Liska V.Vycital O.Levy M.Macinga P.Hucl T.Budinska E.Vodička P.Cordero F.Naccarati A. Published on 2023 Metadata Gastroenterology. 2023 May 30;S0016-5085(23)00811-9. doi: 10.1053/j.gastro.2023.05.037. Online ahead of print.

Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

 DepartmentDepartment of the Molecular Biology of Cancer AutořiThomas M.Qu C.Wang X.Huyghe J. R.Joo J. E.Georgeson P.Arndt V.Berndt S. I.Bézieau S.Bien S. A.Bishop D. T.Brenner H.Brezina S.Burnett-Hartman A.Campbell P. T.Casey G.Castellví-Bel S.Chan A. T.Chang-Claude J.Chen X.Conti D. V.Cremolini C.Diergaarde B.Figueiredo J. C.FitzGerald L. M.Gago-Dominguez M.Gallinger S.Giles G. G.Gsu A.Gunter M. J.Hampe J.Hampel H.Harrison T. A.Hoffmeister M.Keku T. O.Kundaje A.Le Marchand L.Lenz H.-J.Li C. I.Li L.Lin Y.Lindblom A.Moreno V.Murphy N.Newcomb P. A.Newton C. C.Obón-Santacana M.Ogino S.Pai R. K.Palmer J. R.Pearlman R.Pharoah P. D. P.Phipps A. I.Platz E. A.Potter J. D.Rennert G.Sakoda L. C.Schafmayer C.Schmit S. L.Schoen R. E.Slattery M. L.Stadler Z. K.Steinfelder R. S.Thibodeau S. N.Ulrich C. M.Um C. Y.van Duijnhoven F. J. B.Van Guelpen B.Visvanathan K.Vodička P.Vodičková L.Vymetálková V.Weinstein S. J.White E.Winship I. M.Wolk A.Gruber S. B.Jenkins M. A.Hsu L.Buchanan D. D.Peters U. Published on 2023 Metadata Gastroenterology . 2023 Jul 14;S0016-5085(23)04770-4. doi: 10.1053/j.gastro.2023.06.032. Online ahead of print.

Altered hearing function in mice with implanted cranial windows.

 DepartmentDepartment of Auditory Neuroscience AutořiJovanovič N.Suchánková S.Kang M.Melichar A.Bureš Z.Tureček R. Published on 2023 Metadata Neuroscience Letters. 792: 136969.

Association between a polymorphic variant in the CDKN2B-AS1/ANRIL gene and pancreatic cancer risk.

 DepartmentDepartment of the Molecular Biology of Cancer AutořiGiaccherini M.Farinella R.Gentiluomo M.Mohelnikova-Duchonová B.Kauffmann E.F.Palmeri M.Uzunoglu F.Souček P.Petrauskas D.Cavestro G.M.Zykus R.Carrara S.Pezzilli R.Puzzono M.Szentesi A.Neoptolemos J.Archibugi L.Palmieri O.Milanetto A.C.Capurso G.van Eijck C.H.J. Stocker H.Lawlor R.T.Vodička P.Loveček M.Izbicki J. R.Perri F.Kupcinskaite-Noreikiene R.Gotz M.Kupcinskas J.Hussein T.Hegyi P.Busch O.R.Hackert T.Mambrini A.Brenner H.Lucchesi M.Basso D.Tavano F.Schottker B.Vanella G.Bunduc S.Petranyi A.Landi S.Morelli L.Canzian F.Campa D. Published on 2023 Metadata International Journal of Cancer. 153(2): 373-379.

Omne vivum ex ovo: the oocyte reprogramming and remodeling activities.

 DepartmentDepartment of Cell Nucleus Plasticity AutořiFulka H.Loi P.Czernik M.Surani A.Fulka Jr. J. Published on 2023 Metadata Reproduction. 165(3): R75-R89.

Effects of antimicrobial metal nanoparticles on characteristics and function properties of mouse mesenchymal stem cells.

 DepartmentDepartment of Nanotoxicology and Molecular Epidemiology AutořiEchalar B.Dostalová D.Palacká K.Javorková E.Heřmánková B.Červená T.Zajícová A.Holáň V.Rössner P. Published on 2023 Metadata Toxicology in Vitro. 87: 105536.
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