Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

View more

Martin Andrš: Between the lab and the finish line

Interview Published on 08. 10. 2026 Reading time: 10 minutes

Neuroclub is growing. The IEM CAS is now part of it

Professional EventsSeminar Published on 06. 10. 2026 Reading time: 1 minute

Prague.bio 2026: Kristýna Kárová at the interface between science and the biotech industry

ConferenceProfessional Events Published on 02. 10. 2026 Reading time: 1 minute

ICEM 2026: Natálie Danešová represented the IEM CAS in Edinburgh

ConferenceProfessional Events Published on 01. 10. 2026 Reading time: 1 minute

From animal models to data: Scientific training course showcases modern imaging methods in preclinical research

CourseProfessional Events Published on 11. 09. 2026 Reading time: 2 minutes

Toxicologist Pavel Rössner discusses the health effects of air pollution on Studio 6

InterviewMédia Published on 09. 09. 2026 Reading time: 2 minutes
View more

Events

View more

22. 10. 2026

Distinguished Guest Seminar Series – Simon Grelet

Professional EventsSeminarSpecial Guest

05. 11. 2026

Institutional Seminar Series 11/2026

Professional EventsSeminar

08. 12. 2026 - 09. 12. 2026

Introduction to programming for image processing

CourseCzech-BioimagingMicroscopy
View more

About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2023 – 2024 (pdf, 28616 kB)
  • 1975 Established
  • 220 Employees
  • 31 Projects
  • 79 Publications (2025)

Research Departments and Centres

View more

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Genome Biology

Research department

Head of Department

Martin Andrš

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Cellular Neurophysiology

Research Department

Head of the Department

Jana Turečková

Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Neurogenetics

Research Department

Head of the Department

Lenka Šlachtová

View more

Latest Publications

View more

Tissue Dissociation Workflows Influence Reactive Astrocyte Recovery in Single-Cell Transcriptomics

 Department of Cellular Neurophysiology Department of Neuroregeneration AutořiDostalova D.Abaffy P.Matusova Z.Kriška J.Knotek T.Kirdajova D.Turečková J.Pavlicek M.Jendelová P.Anděrová M.Valihrach L. Published on 2026 Metadata Mol Neurobiol . 2026 Oct 16;63(1):974. doi: 10.1007/s12035-026-06278-w.

Meis2 transcription factor regulates craniofacial osteogenesis via IGF signaling and cell adhesion

 Department of Developmental Biology AutořiHudáčová E. Daniel ZuchaKaplan M.Machoň O. Published on 2026 Metadata Bone. 2026 Aug 31:213:118075. doi: 10.1016/j.bone.2026.118075. Online ahead of print.

An Intact PHD Finger and PHD-BRD Interdomain Linker Are Crucial for Binding of the Chromatin Remodeler Factor TIP5 to the Histone Octamer

 Department of Cell Nucleus Plasticity AutořiČabart P. Published on 2026 Metadata Biomolecules 2026, 16(8), 1209; https://doi.org/10.3390/biom16081209

Transcriptional responses to real-world ambient air pollution in healthy and asthmatic human 3D airway models grown at the air-liquid interface

 Department of Toxicology and Molecular Epidemiology AutořiŠímová Z.Líbalová H.Šíma M.Vrbová K.Červená T.Vimrová A.Dittrich L.Vojtíšek M.Pechout M.Klema J.Rössnerová A.Rössner P. Published on 2026 Metadata Journal of Hazardous Materials Advances Volume 23, August 2026, 101404, https://doi.org/10.1016/j.hazadv.2026.101404

Should posthumously retrieved mammalian spermatozoa be evaluated via interspecific ICSI?

 Department of Cell Nucleus Plasticity AutořiVackova K.Rychtarova J.Fulka H.Fulka Jr. J. Published on 2026 Metadata J Assist Reprod Genet . 2026 Jul 10. doi: 10.1007/s10815-026-03970-7. Online ahead of print.

PARG inhibition reduces ssDNA levels and limits RPA loading upon replication fork collapse

 Department of Genome Biology AutořiMihuț A.Ghosh D.Kószó A.Szüts D.Andrs Salajkova S.Andrš M.Dobrovolná J.Fajka-Boja R.Timinszky G. Published on 2026 Metadata EMBO Rep . 2026 Jul 4. doi: 10.1038/s44319-026-00848-8. Online ahead of print.

CEMIP1 and TACSTD2 as circulating mRNA biomarkers for early detection and tumor burden assessment in colorectal neoplasia

 Department of Molecular Biology of Cancer AutořiBalounová K.Uttarilli A.Horák J.Makajevova V.Sojka L.Simsa J.Bruha J.Liska V.Selvi S.Korenkova V.Vodenková S.Jungwirth J.Macinga P.Hucl T.Kral J.Schneiderova M.Valíčková (Šišková) A.Vymetálková V. Published on 2026 Metadata Mol Med . 2026 Jun 25. doi: 10.1186/s10020-026-01537-x. Online ahead of print.

Elongation of spinal cord reactive astrocytes via LRP1/TRK signaling

 Department of Neuroregeneration AutořiRodriguez-Jimenez F. R.Selles F.Jendelová P.Erceg S. Published on 2026 Metadata Signal Transduct Target Ther . 2026 Jun 1;11(1):206. doi: 10.1038/s41392-026-02660-1.

Molecular alterations in human olfactory mucosal cells from healthy individuals and individuals with Alzheimer's disease induced by real-world ambient air

 Department of Toxicology and Molecular Epidemiology AutořiRössner P.Líbalová H.Šíma M.Červená T.Šímová Z.Vrbová K.Ambrož A.Rössnerová A.Nováková Z.Elzeinová F.Vimrová A.Klema J.Koivisto A.M.Penttilä E.Dittrich L.Vojtisek M.Pechout M.Kanninen K.M.Vojtisek-Lom M. Published on 2026 Metadata Environ Toxicol Pharmacol . 2026 Jun:124:105019. doi: 10.1016/j.etap.2026.105019. Epub 2026 Apr 12.
View more