Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

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Vesmír magazine – Special annual issue: The history, present and future of the IEM CAS

OtherPopularisation of Science Published on 08. 01. 2025 Reading time: 2 minutes

New international study: Scientists from the IEM CAS investigated the effect of air pollution on Alzheimer's patients

PublicationResearch Published on 07. 01. 2025 Reading time: 3 minutes

IEM CAS and Bioinova have obtained a European patent for a special solution for the preservation and application of stem cells

PatentsResearch Published on 03. 01. 2025 Reading time: 2 minutes

IEM CAS celebrates its 50-year anniversary

AnniversaryResearch Published on 01. 01. 2025 Reading time: 3 minutes

Merry Christmas and a Happy New Year

Other Published on 24. 12. 2024 Reading time: 1 minute

A new paper by scientists from the IEM CAS and the IBT CAS uncovers the link between mitochondrial DNA and carcinogenesis

PublicationResearch Published on 20. 12. 2024 Reading time: 3 minutes
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Events

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16. 01. 2025

Institutional Seminar Series 1/2025

Professional EventsSeminar

06. 02. 2025

Institutional Seminar Series 2/2025

Professional EventsSeminar

10. 03. 2025 - 16. 03. 2025

Week of the Brain – Czech Academy of Sciences

Popularisation of Science

02. 06. 2025 - 05. 06. 2025

53rd European Environment Mutagenesis and Genomics Society Meeting

ConferenceProfessional Events
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2021-2022 (pdf, 46372 kB)
  • 1975 Established
  • 220 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

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Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

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Latest Publications

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The Influence of Asymmetric Hearing Loss on Peripheral and Central Auditory Processing Abilities in Patients With Vestibular Schwannoma

 Autoři Published on 2025 Metadata Ear Hear. 2025 Jan-Feb;46(1):60-70. doi: 10.1097/AUD.0000000000001555. Epub 2024 Jul 15.

Characterization of additive gene-environment interactions for colorectal cancer risk

 AutořiThomas C.E.Lin Y.Kim M.Kawaguchi E.S.Qu C.Um C.Y.Lynch B.M.Van Guelpen B.Tsilidis K.Carreras-Torres R.van Duijnhoven F.J.B.Sakoda L.C.Campbell P.T.Tian Y.Chang-Claude J.Bézieau S.Budiarto A.Palmer J.R.Newcomb P.A.Casey G.Le Marchand L.Giannakis M.Li C.I.Gsur A.Newton C.Obón-Santacana M.Moreno V.Brenner H.Hoffmeister M.Pellatt A.J.Schoen R.E.Dimou N.Murphy N.Gunter M.J.Castellví-Bel S.Figueiredo J.C.Chan A.T.Song M.Li L.Bishop D.T.Gruber S.B.Baurley J.W.Bien S.A.Conti D.V.Huyghe J.R.Kundaje A.Su Y.-R.Wang J.Keku T.O.Woods M.O.Berndt S.I.Chanock S.J.Tangen C.M.Wolk A.Burnett-Hartman A.Wu A.H.White E.Devall M.A.Díez-Obrero V.Drew D.A.Giovannucci E.Hidaka A.Kim A.E.Lewinger J.P.Morrison J.Ose J.Papadimitriou N.Pardamean B.Peoples A.R.Ruiz-Narvaez E.A.Shcherbina A.Stern M.C.Chen X.Thomas D.C.Platz E.A.Gauderman W.J.Peters U.Hsu L. Published on 2025 Metadata Epidemiology. 2025 Jan 1;36(1):126-138. doi: 10.1097/EDE.0000000000001795. Epub 2024 Sep 24.

Transcriptomic and epigenomic profiling reveals alteredresponses to diesel emissions in Alzheimer’s disease both invitro and in population-based data

 Department of Toxicology and Molecular Epidemiology AutořiSaveleva L.Červená T.Mengoni C.Šíma M.Krejčík Z.Vrbová K.Sikorová J.Mussalo L.de Crom T. O. E.Šímová Z.Ivanova M.Shahbaz M. A.Penttilä E.Löppönen H.Koivisto A. M.Ikram M. A.Jalava P. I.Malm T.Chew S.Vojtíšek M.Topinka J.Giugno R.Rössner P.Kanninen K. M. Published on 2024 Metadata Alzheimers Dement . 2024 Dec 24. doi: https://doi.org/10.1002/alz.14347.

The Cwr1 protein kinase localizes to the plasma membrane and mediates resistance to cell wall stress in Candida albicans

 AutořiNaseem S.Zahumenský J.Lanze C. E.Malínský J.Konopka J. B. Published on 2024 Metadata mSphere. 2024 Dec 19;9(12):e0039124. doi: 10.1128/msphere.00391-24. Epub 2024 Nov 29.

Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects

 Department of Neurochemistry AutořiKonecny J.Misiachna A.Chvojkova M.Kletečková L.Kolcheva M.Novak M.Prchal L.Ladislav M.Hemelíková K.Netolický J.Hrabinova M.Kobrlova T.Zdarova Karasova J.Pejchal J.Fibigar J.Vecera Z.Kucera T.Jendelová P.Baráčková P.Langore E.Doderović J.Pang Y.P.Valeš K.Korabecny J.Soukup O.Horák M. Published on 2024 Metadata Eur J Med Chem . 2024 Dec 15:280:116981. doi: 10.1016/j.ejmech.2024.116981. Epub 2024 Oct 18.

Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation

 Department of Developmental Biology AutořiKaplan M.Hudáčová E.Matějček M.Tuaima H.Krivanek J.Machoň O. Published on 2024 Metadata eLife13:RP100854 https://doi.org/10.7554/eLife.100854.1

Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia

 Department of Cellular Neurophysiology AutořiZucha D.Abaffy P.Kirdajová D.Jirak D.Kubista M.Anděrová M.Valihrach L. Published on 2024 Metadata Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2404203121. doi: 10.1073/pnas.2404203121. Epub 2024 Nov 5.

The effect of acoustically enriched environment on structure and function of the developing auditory system

 Department of Auditory Neuroscience AutořiBureš Z.Svobodová Burianová J.Pysanenko K.Syka J. Published on 2024 Metadata Hear Res . 2024 Nov:453:109110. doi: 10.1016/j.heares.2024.109110. Epub 2024 Sep 5.

Neuronal maturation and axon regeneration: unfixing circuitry to enable repair

 Centre for Reconstructive Neuroscience AutořiHilton B. J.Griffin J. M.Fawcett J.Bradke F. Published on 2024 Metadata Nat Rev Neurosci . 2024 Oct;25(10):649-667. doi: 10.1038/s41583-024-00849-3. Epub 2024 Aug 20.
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