Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

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Research

Study & Careers


News

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PhD students from the IEM CAS were successful in the GA UK grant competition: Five projects succeeded

GrantsProject Published on 16. 04. 2025 Reading time: 10 minutes

Interview in CNN Prima News magazine: Cancer does not choose, says geneticist Veronika Vymetálková

ArticleInterview Published on 11. 04. 2025 Reading time: 3 minutes

Neuroscientist Miroslava Anděrová has become the new Vice-President of the CAS

AwardOther Published on 03. 04. 2025 Reading time: 1 minute

IARC results of the international assessment – Gasoline newly classified as a proven carcinogen

PublicationResearch Published on 28. 03. 2025 Reading time: 3 minutes

The Academic Council of the CAS has elected the members of the Academy and Science Councils. Among them are Miroslava Anděrová, Director of the IEM CAS, and neuroscientist Pavla Jendelová

Award Published on 18. 03. 2025 Reading time: 2 minutes

Interview with toxicologists Jan Topinka and Kateřina Hoňková on Czech Television

InterviewTV Report Published on 16. 03. 2025 Reading time: 3 minutes
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Events

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29. 04. 2025

μLectures: Olympus SpinSR10 tips & tricks

Czech-BioimagingMicroscopyμLectures

22. 05. 2025 - 23. 05. 2025

Advanced 3D image visualization and quantification

CourseCzech-BioimagingMicroscopy

02. 06. 2025 - 05. 06. 2025

53rd European Environment Mutagenesis and Genomics Society Meeting

ConferenceProfessional Events

08. 09. 2025 - 12. 09. 2025

Advanced Course on Preclinical Imaging

CourseCzech-BioimagingMicroscopy

12. 11. 2025 - 14. 11. 2025

Introduction to Programming for Image Processing

CourseCzech-BioimagingMicroscopy
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2021-2022 (pdf, 46372 kB)
  • 1975 Established
  • 219 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

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Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

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Latest Publications

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Hyperactive delta isoform of PI3 kinase enables long-distance regeneration of adult rat corticospinal tract

 Department of Neuroregeneration Department of Auditory Neuroscience AutořiKárová K.Polčanová Z.Knight L.Suchánková S.Nieuwenhuis B.Holota R.Herynek V.Urdzíková-Machová L.Tureček R.Kwok J.C.F.Herik J. vdVerhaagen J.Eva R.Fawcett J.Jendelová P. Published on 2025 Metadata Mol Ther. 2025 Feb 5;33(2):752-770. doi: 10.1016/j.ymthe.2024.12.040. Epub 2025 Jan 1.

Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety

 Department of Auditory Neuroscience AutořiPérez-Garci E.Pysanenko K.Rizzi G.Studer F.Ulrich D.Fritzius T.Früh S.Porcu A.Besseyrias V.Melichar A.Gassmann M.Barkat T. R.Tureček R.Tan K. R.Bettler B. Published on 2025 Metadata Neurobiol Dis. 2025 Feb 4:206:106831. doi: 10.1016/j.nbd.2025.106831. Online ahead of print.

Prophylaxis by a reversible cholinesterase inhibitor and the NMDA receptor antagonist treatment as combinatorial countermeasure against nerve agent poisoning in mice model

 Department of Neurochemistry AutořiKassa J.Konecny J.Svobodova B.Horák M.Korabecny J.Soukup O. Published on 2025 Metadata Chem Biol Interact . 2025 Feb 1:407:111386. doi: 10.1016/j.cbi.2025.111386. Epub 2025 Jan 11.

Perspectives and Limitations of Mesenchymal Stem Cell-Based Therapy for Corneal Injuries and Retinal Diseases

 Department of Toxicology and Molecular Epidemiology AutořiHeřmánková B.Javorková E.Palacká K.Holáň V. Published on 2025 Metadata Cell Transplant . 2025 Jan-Dec:34:9636897241312798. doi: 10.1177/09636897241312798

Topical siRNA therapy of diabetic-like wound healing

 Department of Tissue Engineering AutořiNeuhoferova E.Kindermann M.Buzgo M.Vocetková K.Panek D. Cigler P.Benson V. Published on 2025 Metadata J Mater Chem B . 2025 Jan 15;13(3):1037-1051. doi: 10.1039/d4tb01547a.

Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization

 Department of Molecular Biology of Cancer AutořiGálvez-Montosa F.Peduzzi G.Sanchez-Maldonado J. M.Horst R. T.Cabrera-Serrano A. J.Gentiluomo M.Macauda A.Luque N.Ünal P.García-Verdejo F. J.Li Y.López J. A. L.Stein A.Bueno-de-Mesquita H. B.Arcidiacono P. G....Vodičková L....Dohan O.Tacelli M.Greenhalf W.Gazouli M.Neoptolemos J. P.Cavestro G. M.Boggi U.Latiano A.Hegyi P.Ginocchi L.Netea M. G.Sánchez-Rovira P.Canzian F.Campa D.Sainz J. Published on 2025 Metadata Int J Cancer. 2025 Jan 15;156(2):339-352. doi: 10.1002/ijc.35196. Epub 2024 Sep 25.

Portable emissions toxicity system: Evaluating the toxicity of emissions or polluted air by exposure of cell cultures at air-liquid interface in a compact field-deployable setup

 Department of Toxicology and Molecular Epidemiology AutořiVojtíšek M.Dittrich L.Pechout M.Červená T.Vimrová A.Sikorová J.Závodná T.Ondracek J.Aakko-Saksa P.Topinka J.Rössner P. Published on 2025 Metadata Sci Total Environ. 2025 Jan 10:959:178010. doi: 10.1016/j.scitotenv.2024.178010. Epub 2024 Dec 21.

The Influence of Asymmetric Hearing Loss on Peripheral and Central Auditory Processing Abilities in Patients With Vestibular Schwannoma

 Department of Auditory Neuroscience AutořiSvobodova V.Profant O.Syka J.Tóthová D.Bureš Z. Published on 2025 Metadata Ear Hear. 2025 Jan-Feb;46(1):60-70. doi: 10.1097/AUD.0000000000001555. Epub 2024 Jul 15.

Real-world outdoor air exposure effects in a model of the human airway epithelium - A comparison of healthy and asthmatic individuals using a mobile laboratory setting

 Department of Toxicology and Molecular Epidemiology AutořiRössner P.Líbalová H.Červená T.Šíma M.Šímová Z.Vrbová K.Ambrož A.Nováková Z.Elzeinová F.Vimrová A.Dittrich L.Vojtisek M.Pechout M.Vojtisek-Lom M. Published on 2025 Metadata Ecotoxicol Environ Saf. 2025 Jan 1:289:117495. doi: 10.1016/j.ecoenv.2024.117495. Epub 2024 Dec 7.
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