30. 06. 2023
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The prestigious journal of the Society for Neuroscience, The Journal of Neuroscience, has published a new co-authored article with the participation of neuroscientists from the IEM CAS, namely Pavla Jendelová and Anda Cimpean. In addition, the article was also mentioned in the “Featured Research Page“, and on the Society of Neuroscience social media.
The study was created in collaboration with James Fawcett from the University of Cambridge, who leads the Center for Reconstructive Neuroscience at the IEM CAS and is concerned with the mechanisms of axon regeneration. The aim was to use mRNA sequencing in regenerating sensory neurons to determine which mechanisms are activated during nerve fibre regeneration. Surprisingly, not the same regeneration programme as in peripheral nerves or during embryonic development was activated, but rather mechanisms related to autophagy, ubiquitination, and endoplasmic reticulum modulation.
The full results of the study can be found on the website www.jneurosci.org (open in a new window).