Department

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes

 DepartmentDepartment of Neurochemistry AutořiKortus S.Řeháková K.Klima M.Kolcheva M.Ladislav M.Langore E.Baráčková P.Netolický J.Misiachna A.Hemelíková K.Humpolickova J.Chalupska D.Silhan J.Kaniaková M.Hrčka Krausová B.Boura E.Zapotocky M.Horák M. Published on 2023 Metadata J Neurosci. 2023 Jun 28;43(26):4755-4774. doi: 10.1523/JNEUROSCI.2014-22.2023. Epub 2023 Jun 7.

Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors.

 DepartmentDepartment of Neurochemistry AutořiKolcheva M.Kortus S.Hrčka Krausová B.Baráčková P.Misiachna A.Danačíková Š.Kaniaková M.Hemelíková K.Hotovec M.Řeháková K.Horák M. Published on 2021 Metadata Neuropharmacology. 189: 108528.

7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo.

 DepartmentDepartment of Neurochemistry AutořiKaniaková M.Korábečný J.Holubová K.Kletečková L.Chvojková M.Hakenová K.Prchal L.Novák M.Doležal R.Hepnarová V.Svobodová B.Kučera T.Lichnerová K.Hrčka Krausová B.Horák M.Valeš K.Soukup O. Published on 2021 Metadata Biochemical Pharmacology. 186: 114460.

The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.

 DepartmentDepartment of Neurochemistry AutořiKolcheva M.Ladislav M.Netolický J.Kortus S.Řeháková K.Hrčka Krausová B.Hemelíková K.Misiachna A.Kádková A.Klíma M.Chalupská D.Horák M. Published on 2023 Metadata Neuropharmacology. 222: 109297.