Res. Prof. Pavel Vodička, M.D.

Mitochondrial DNA damage, repair, and replacement in cancer

Department of Molecular Biology of Cancer Vodička P.Vodenková S.Danešová N.Vodičková L.Zobalova R.Tomášová K.Boukalova S.Berridge M. V.Neuzil J. 2024 Trends Cancer. 2024 Oct 21:S2405-8033(24)00212-7. doi: 10.1016/j.trecan.2024.09.010. Online ahead of print.

Haplotype analysis identifies functional elements in monoclonal gammopathy of unknown significance

Department of Molecular Biology of Cancer Thomsen H.Chattopadhyay S.Weinhold N.Vodička P.Vodičková L.Hoffmann P.Nöthen M.M.Jöckel K.H.Schmidt B.Hajek R.Hallmans G.Pettersson-Kymmer U.Späth F.Goldschmidt H.Hemminki K.Försti A. 2024 Blood Cancer J . 2024 Aug 20;14(1):140. doi: 10.1038/s41408-024-01121-8.

Large-Scale Alternative Polyadenylation-Wide Association Studies to Identify Putative Cancer Susceptibility Genes

Department of Molecular Biology of Cancer Guo X.Ping J.Yang Y.Su X.Shu X.Wen W.Chen Z.Zhang Y.Tao R.Jia G.He J.Cai Q.Zhang Q.Giles G.Pearlman R.Rennert G.Vodička P.Phipps A.Gruber S.Casey G.Peters U.Long J.Lin W.Zheng W. 2024 Cancer Res . 2024 Aug 15;84(16):2707-2719. doi: 10.1158/0008-5472.CAN-24-0521.

Deciphering the genetics and mechanisms of predisposition to multiple myeloma

Department of Molecular Biology of Cancer Went M.Duran-Lozano L.Halldorsson G.H.Gunnell A.Ugidos-Damboriena N.Law P.Ekdahl L.Sud A.Thorleifsson G.Thodberg M.Olafsdottir T.Lamarca-Arrizabalaga A.Cafaro C.Niroula A.Ajore R.Lopez de Lapuente Portilla A.Ali Z.Pertesi M.Goldschmidt H.Stefansdottir L.Kristinsson S.Y.Stacey S.N.Love T.J.Rognvaldsson S.Hajek R.Vodička P.Pettersson-Kymmer U.Späth F.Schinke C.Van Rhee F.Sulem P.Ferkingstad E.Eldjarn G.H.Mellqvist U.H.Jonsdottir I.Morgan G.Sonneveld P.Waage A.Weinhold N.Thomsen H.Försti A.Hansson M.Juul-Vangsted A.Thorsteinsdottir U.Hemminki K.Kaiser M.Rafnar T.Stefansson K.Houlston R.Nilsson B. 2024 Nat Commun . 2024 Aug 5;15(1):6644. doi: 10.1038/s41467-024-50932-7.

Frequencies of chromosomal aberrations and related biochemical parameters in welders

Department of Molecular Biology of Cancer Vodička P.Musak L.Grendar M.Valachova J.Vodičková L.Halasova E. 2024 Mutat Res Genet Toxicol Environ Mutagen . 2024 Aug-Sep:898:503806. doi: 10.1016/j.mrgentox.2024.503806. Epub 2024 Jul 25.

Telomere length as a predictor of therapy response and survival in patients diagnosed with ovarian carcinoma

Department of Molecular Biology of Cancer Tomášová K.Seborova K.Kroupa M.Horák J.Kavec M.Vodičková L.Rob L.Hruda M.Mrhalova M.Bartakova A.Bouda J.Fleischer T.Kristensen V. N.Vodička P.Vaclavikova R. 2024 Heliyon . 2024 Jun 29;10(13):e33525. doi: 10.1016/j.heliyon.2024.e33525. eCollection 2024 Jul 15.

Fecal miRNA profiles in colorectal cancers with mucinous morphology

Department of Molecular Biology of Cancer Naccarati A.Dragomir M. P.Tarallo S.Gagliardi A.Alberini V.Buchler T.Gallo G.Vymetálková V.Vodičková L.Vodička P.Pardini B.Ferrero G. 2024 Mutagenesis . 2024 Jun 6:geae015. doi: 10.1093/mutage/geae015. Online ahead of print.

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction

Department of Molecular Biology of Cancer Schormair B.Zhao Ch.Bell S.Didriksen M.Nawaz M. S.Schandra N.Stefani A.Högl B.Dauvilliers Y.Bachmann C. G.Kemlink D.Sonka K.Paulus W.Trenkwalder C.Oertel W. H.Hornyak M.Teder-Laving M.Metspalu A.Hadjigeorgiou G. M.Polo O.Fietze I.Ross O. A.Wszolek Z. K.Ibrahim A.Bergmann M.Kittke V.Harrer P.Dowsett J.Chenini S.Ostrowski S. R.Sørensen E.Erikstrup C.Pedersen O. B.Bruun M. T.Nielsen K. R.Butterworth A. S.Soranzo N.Ouwehand W. H.Roberts D. J.Danesh J.Burchell B.Furlotte N. A.Nandakumar P.Earley C. J.Ondo W. G.Xiong L.Desautels A.Perola M.Vodička P.Dina C.Stoll M.Franke A.Lieb W.Stewart A. F. R.Shah S. H.Gieger C.Peters A.Rye D. B.Rouleau G. A.Berger K.Stefansson H.Ullum H.Stefansson K.Hinds D. A.Di Angelantonio E.Oexle K.Winkelmann J. 2024 Nat Genet . 2024 Jun;56(6):1090-1099. doi: 10.1038/s41588-024-01763-1. Epub 2024 Jun 5.

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Department of Molecular Biology of Cancer Chen Z.Guo X.Tao R.Huyghe J. R.Law P. J.Fernandez-Rozadilla C.Ping J.Jia G.J. LongLi C....Vodička P.Vodičková L.Vymetálková V....Hsu L.Cai Q.Dunlop M. G.Gruber S. B.Houlston R. S.Moreno V.Casey G.Peters U.Tomlinson I.Zheng W. 2024 Nat Commun . 2024 Apr 26;15(1):3557. doi: 10.1038/s41467-024-47399-x.

A pleiotropy scan to discover new susceptibility loci for pancreatic ductal adenocarcinoma

Department of Molecular Biology of Cancer Giaccherini M.Rende M.Gentiluomo M.Corradi C.Archibugi L.Ermini S.Maiello E.Morelli L.van Eijck C. H. J.Cavestro G. M.Schneider M.Mickevicius A.Adamonis K.Basso D.Hlavac V....Vodička P....Stocker S.Neoptolemos J. P.Bambi F.Jamroziak K.Testoni S. G. G.Aoki M. N.Mohelnikova-Duchonova B.Izbicki J. R.Pezzilli R.Lawlor R. T.Kauffmann E. F.de Maturana E. L.Malats N.Canzian F.Campa D. 2024 Mutagenesis. 2024 Apr 12:geae012. doi: 10.1093/mutage/geae012. Online ahead of print.

Commentary: Special Issue - Current Understanding of Colorectal and Pancreatic Cancers

Department of Molecular Biology of Cancer Vodička P.Vodičková L. 2024 Mutagenesis . 2024 Mar 29:geae009. doi: 10.1093/mutage/geae009. Online ahead of print.

Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations

Department of Molecular Biology of Cancer Hemminki K.Niazi Y.Vodičková L.Vodička P.Försti A. 2024 Mutagenesis. 2024 Feb 29:geae006. doi: 10.1093/mutage/geae006. Online ahead of print.

Genome-wide association study and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer

Department of Molecular Biology of Cancer Laskar R.S.Qu C.Huyghe J.R.Harrison T.Hayes R.B.Cao Y.Campbell P.T.Steinfelder R.Talukdar F.R.Brenner H.Ogino S.Brendt S.Bishop D.T.Buchanan D.D.Chan A.T.Cotterchio M.Gruber S.B.Gsur A.van Guelpen B.Jenkins M.A.Keku T.O.Lynch B.M.Le Marchand L.Martin R.M.McCarthy K.Moreno V.Pearlman R.Song M.Tsilidis K.K.Vodička P.Woods M.O.Wu K.Hsu L.Gunter M.J.Peters U.Murphy N. 2024 Ann Oncol . 2024 Feb 24:S0923-7534(24)00058-9. doi: 10.1016/j.annonc.2024.02.008. Online ahead of print.

Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation

Department of Molecular Biology of Cancer Chen Z.Song W.Shu X.-O.Wen W.Devall M.Dampier C.Moratalla-Navarro F.Cai Q.Long J.Van Kaer L.Wu L.Huyghe J. R.Thomas M.Hsu L.Woods M. O.Albanes D.Buchanan D. D.Gsur A.Hoffmeister M.Vodička P.Wolk A.Le Marchand L.Wu A. H.Phipps A. I.Moreno V.Peters U.Zheng W.Casey G.Guo X. 2024 J Natl Cancer Inst . 2024 Jan 10;116(1):127-137. doi: 10.1093/jnci/djad178.

Genetic and non-genetic risk factors for early-onset pancreatic cancer

Department of Molecular Biology of Cancer Nodari Y.Gentiluomo M.Mohelnikova-Duchonova B.Kreivenaite E.Milanetto A. C.Skieceviciene J.Landi S.Lawlor R. T.Petrone M. C.Arcidiacono P. G....Vodička P....Capurso G.Perri F.Ermini S.Theodoropoulos G.Capretti G.Palmieri O.Ginocchi L.Furbetta N.Canzian F.Campa D. 2023 Dig Liver Dis . 2023 Oct;55(10):1417-1425. doi: 10.1016/j.dld.2023.02.023. Epub 2023 Mar 25.

Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

Department of Molecular Biology of Cancer Thomas M.Qu C.Wang X.Huyghe J. R.Joo J. E.Georgeson P.Arndt V.Berndt S. I.Bézieau S.Bien S. A.Bishop D. T.Brenner H.Brezina S.Burnett-Hartman A.Campbell P. T.Casey G.Castellví-Bel S.Chan A. T.Chang-Claude J.Chen X.Conti D. V.Cremolini C.Diergaarde B.Figueiredo J. C.FitzGerald L. M.Gago-Dominguez M.Gallinger S.Giles G. G.Gsu A.Gunter M. J.Hampe J.Hampel H.Harrison T. A.Hoffmeister M.Keku T. O.Kundaje A.Le Marchand L.Lenz H.-J.Li C. I.Li L.Lin Y.Lindblom A.Moreno V.Murphy N.Newcomb P. A.Newton C. C.Obón-Santacana M.Ogino S.Pai R. K.Palmer J. R.Pearlman R.Pharoah P. D. P.Phipps A. I.Platz E. A.Potter J. D.Rennert G.Sakoda L. C.Schafmayer C.Schmit S. L.Schoen R. E.Slattery M. L.Stadler Z. K.Steinfelder R. S.Thibodeau S. N.Ulrich C. M.Um C. Y.van Duijnhoven F. J. B.Van Guelpen B.Visvanathan K.Vodička P.Vodičková L.Vymetálková V.Weinstein S. J.White E.Winship I. M.Wolk A.Gruber S. B.Jenkins M. A.Hsu L.Buchanan D. D.Peters U. 2023 Gastroenterology. 2023 Oct;165(4):1070-1076.e3. doi: 10.1053/j.gastro.2023.06.032. Epub 2023 Jul 14.

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Department of Molecular Biology of Cancer Thomas M.Su Y-R.Rosenthal E. A.Sakoda L. C.Schmit S. L.Timofeeva M. N.Chen Z.Fernandez-Rozadilla C.Law P. J.Murphy N.Carreras-Torres R.Diez-Obrero V.van Duijnhoven F. J. B.Jiang S.Shin A.Wolk A.Phipps A. I.Burnett-Hartman A.Gsur A.Chan A. T.Zauber A. G.Wu A. H.Lindblom A.Um C. Y.Tangen C. M.Gignoux C.Newton C.Haiman C. A.Qu C.Bishop D. T.Buchanan D. D.Crosslin D. R.Conti D. V.Kim D-H.Hauser E.White E.Siegel E.Schumacher F. R.Rennert G.Giles G. G.Hampel H.Brenner H.Oze I.Oh J. H.Lee J. K.Schneider J. L.Chang-Claude J.Kim J.Huyghe J. R.Zheng J.Hampe J.Greenson J.Hopper J. L.Palmer J. R.Visvanathan K.Matsuo K.Matsuda K.Jung K. J.Li L.Le Marchand L.Vodičková L.Bujanda L.Gunter M. J.Matejcic M.Jenkins M. A.Slattery M. L.D'Amato M.Wang M.Hoffmeister M.Woods M. O.Kim M.Song M.Iwasaki M.Du M.Udaltsova N.Sawada N.Vodička P.Campbell P. T.Newcomb P. A.Cai Q.Pearlman R.Pai R. K.Schoen R. E.Steinfelder R. S.Haile R. W.Vandenputtelaar R.Prentice R. L.Küry S.Castellví-Bel S.Tsugane S.Berndt S. I.Lee S. C.Brezina S.Weinstein S. J.Chanock S. J.Jee S. H.Kweon S-S.Vadaparampil S.Harrison T. A.Yamaji T.Keku T. O.Vymetálková V.Arndt V.Jia W-H.Shu X-O.Lin Y.Ahn Y-O.Stadler Z. K.Van Guelpen B.Ulrich C. M.Platz E. A.Potter J. D.Li C. I.Meester R.Moreno V.Figueiredo J. C.Casey G.Lansdorp Vogelaar I.Dunlop M. G.Gruber S. B.Hayes R. B.Pharoah P. D.Houlston R. S.Jarvik G. P.Tomlinson I. P.Zheng W.Corley D. A.Peters U.Hsu L. 2023 Nat Commun. 2023 Oct 2;14(1):6147. doi: 10.1038/s41467-023-41819-0.

Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses

Department of Molecular Biology of Cancer Dimou N.Kim A. E.Flanagan O.Murphy N.Diez-Obrero V.Shcherbina A.Aglago E. K.Bouras E.Campbell P. T.Casey G....Vodička P.Vodičková L.White E.Wolk A.Woods M. O.Qu C.Kundaje A.Hsu L.Gauderman W. J.Gunter M. J.Peters U. 2023 Br J Cancer . 2023 Aug;129(3):511-520. doi: 10.1038/s41416-023-02312-z. Epub 2023 Jun 26.

A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk

Department of Molecular Biology of Cancer Aglago E. K.Kim A. E.Lin Y.Qu C.Evangelou M.Ren Y.Morrison J.Albanes D.Arndt V.Barry E. L.Baurley J. W.Berndt S. I.Bien S. A.Bishop D. T.Bouras E.Brenner H.Buchanan D. D.Budiarto A.Carreras-Torres R.Casey G.Cenggoro T. W.Chan A. T.Chang-Claude J.Chen X.Conti D. V.Devall M.Díez-Obrero V.Dimou N.Drew D.Figueiredo J. C.Gallinger S.Giles G. G.Gruber S. B.Gsur A.Gunter M. J.Hampel H.Harlid S.Hidaka A.Harrison T. A.Hoffmeister M.Huyghe J. R.Jenkins M. A.Jordahl K.Joshi A. D.Kawaguchi E. S.Keku T. O.Kundaje A.Larsson S. C.Le Marchand L.Lewinger J. P.Li L.Lynch B. M.Mahesworo B.Mandic M.Obón-Santacana M.Moreno V.Murphy N.Nan H.Nassir R.Newcomb P. A.Ogino S.Ose J.Pai R. K.Palmer J. R.Papadimitriou N.Pardamean B.Peoples A. R.Platz E. A.Potter J. D.Prentice R. L.Rennert G.Ruiz-Narvaez E.Sakoda L. C.Scacheri P. C.Schmit S. L.Schoen R. E.Shcherbina A.Slattery M. L.Stern M. C.Su Y. R.Tangen C. M.Thibodeau S. N.Thomas D. C.Tian Y.Ulrich C. M.van Duijnhoven F. J. B.Van Guelpen B.Visvanathan K.Vodička P.Wang J.White E.Wolk A.Woods M. O.Wu A. H.Zemlianskaia N.Hsu L.Gauderman W. J.Peters U.Tsilidis K. K.Campbell P. T. 2023 Cancer Res . 2023 May 30;CAN-22-3713. doi: 10.1158/0008-5472.CAN-22-3713. Online ahead of print.

A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study

Department of Molecular Biology of Cancer Pardini B. Ferrero G.Tarallo S.Gallo G.Francavilla A.Licheri N.Trompetto M.Clerico G.Senore C.Peyre S.Vymetálková V.Vodičková L.Liska V.Vycital O.Levy M.Macinga P.Hucl T.Budinska E.Vodička P.Cordero F.Naccarati A. 2023 Gastroenterology. 2023 May 30;S0016-5085(23)00811-9. doi: 10.1053/j.gastro.2023.05.037. Online ahead of print.

Association between a polymorphic variant in the CDKN2B-AS1/ANRIL gene and pancreatic cancer risk.

Department of Molecular Biology of Cancer Giaccherini M.Farinella R.Gentiluomo M.Mohelnikova-Duchonová B.Kauffmann E.F.Palmeri M.Uzunoglu F.Souček P.Petrauskas D.Cavestro G.M.Zykus R.Carrara S.Pezzilli R.Puzzono M.Szentesi A.Neoptolemos J.Archibugi L.Palmieri O.Milanetto A.C.Capurso G.van Eijck C.H.J. Stocker H.Lawlor R.T.Vodička P.Loveček M.Izbicki J. R.Perri F.Kupcinskaite-Noreikiene R.Gotz M.Kupcinskas J.Hussein T.Hegyi P.Busch O.R.Hackert T.Mambrini A.Brenner H.Lucchesi M.Basso D.Tavano F.Schottker B.Vanella G.Bunduc S.Petranyi A.Landi S.Morelli L.Canzian F.Campa D. 2023 International Journal of Cancer. 153(2): 373-379.

Validation of a Genetic-Enhanced Risk Prediction Model for Colorectal Cancer in a Large Community-Based Cohort.

Department of Molecular Biology of Cancer Su Y.R.Sakoda L.C.Jeon J.Thomas M.Lin Y.Schneider J.L.Udaltsová N.Lee J.K.Lansdorp-Vogelaar I.Peterse E.F.P.Zauber A.G.Zheng J.Y.Zheng Y.Y.Hauser E.Baron J.A.Barry E.L.Bishop D.T.Brenner H.Buchanan D.D.Burnett-Hartman A.Campbell P.T.Casey G.Castellvi-Bel S.Chan A.T.Chang-Claude J.Figueiredo J.C.Gallinger S.J.Giles G.G.Gruber S.B.Gsur A.Gunter M.J.Hampe J.Hampel H.Harrison T.A.Hoffmeister M.Hua X.W.Huyghe J.R.Jenkins M.A.Keku T.O.Le Marchand L.Li L.Lindblom A.Moreno V.Newcomb P.A.Pharoah P.D.P.Platz E.A.Potter J.D.Qu C.Rennert G.Schoen R.E.Slattery M.L.Song M.Y.van Duijnhoven F.J.B.Van Guelpen B.Vodička P.Wolk A.Woods M.O.Wu A.H.Hayes R.B.Peters U.Corley D.A.Hsu L. 2023 Cancer Epidemiology Biomarkers & Prevention. 32(3): 353-362.

Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response.

Department of Molecular Biology of Cancer Carreras-Torres R.Kim A.E.Lin Y.Diez-Obrero V.Bien S.A.Qu C.H.Wang J.Dimou N.Aglago E.K.Albanes D.Arndt V.Baurley J.W.Berndt S.I.Bezieau S.Bishop D.T.Bouras E.Brenner H.Budiarto A.Campbell P.T.Casey G.Chan A.T.Chang-Claude J.Chen X.Conti D.Dampier Ch.Devall M.A.M.Drew D.A.Figueiredo J.C.Gallinger S.Giles G.G.Gruber S.B.Gsur A.Gunter M.J.Harrison T.Hidaka A.Hoffmeister M.Huyghe J.Jenkins M.A.Jordahl K.M.Kawaguchi E.Keku T.O.Kundaje A.Le Marchand L.Lewinger J.P.Li L.Mahesworo B.Morrison J. L.Murphy N.Nan H.Nassir R.Newcomb P.A.Obon-Santacana M.Ogino S.Ose J.Pai R.K.Palmer J.R.Papadimitriou N.Pardamean B.Peoples A.R.Pharoah P.D.P.Platz E.A.Rennert G.Ruiz-Narvaez E.Sakoda L.C.Scacheri P.C.Schmit S.L.Schoen R.E.Shcherbina A.Slattery M.L.Stern M.C.Su Y.R.Tangen C.M.Thomas D.C. Tian Y.Tsilidis K.K.Ulrich C.M.van Duijnhoven F.J.B.Van Guelpen B.Visvanathan K.Vodička P.Cenggoro T.W.Weinstein S. J.White E.Wolk A.Woods M.O.Hsu L.Peters U.Moreno V.Gauderman W.J. 2023 Cancer Epidemiology Biomarkers & Prevention. 32(3): 315-328.

Genetic Susceptibility in Understanding of Pancreatic Ductal Adenocarcinoma Risk: A Decade-Long Effort of the PANDORA Consortium.

Department of Molecular Biology of Cancer Vodičková L.Horák J.Vodička P. 2022 Cancer Epidemiology Biomarkers & Prevention. 31(5): 942-948.

Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients' outcomes.

Department of Molecular Biology of Cancer Tomášová K.Kroupa M.Zinková A.Korabečná M.Vymetálková V.Skrobánek P.Sojka L.Levy M.Hemminki K.Liška V.Hošek P.Kumar R.Vodičková L.Vodička P. 2022 Frontiers in Oncology. 12:962929.

Discovery of Long Non-Coding RNA MALAT1 Amplification in Precancerous Colorectal Lesions.

Department of Molecular Biology of Cancer Šišková A.Král J.Drabová J.Červená K.Tomášová K.Jungwirth J.Hucl T.Kohout P.Summerová S.Vodičková L.Vodička P.Vymetálková V. 2022 International Journal of Molecular Sciences. 23(14): 7656.

Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy.

Department of Molecular Biology of Cancer Šeborová K.Hlaváč V.Holý P.Bjørklund S.Fleischer T.Rob L.Hruda M.Bouda J.Mrhalová M.Al Obeed Allah M.M.Vodičková L.Vodička P.Fiala O.Souček P.Kristensen V.Václavíková R. 2022 Frontiers in Oncology. 12: 1016958.

The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case-Control Studies in Irish and Czech Populations.

Department of Molecular Biology of Cancer Mukhtar M.Ashfield N.Vodičková L.Vymetálková V.Levy M.Liska V.Bruha J.Bendová P.O‘Sullivan J.Doherty G.Sheahan K.Nolan B.Vodička P.Hughes D. 2022 Nutrients. 14(13): 2718.

Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk.

Department of Molecular Biology of Cancer Lu Y.Gentiluomo M.Gioffreda D.Gazouli M.Petrone M. C.Kelemen D.Ginocchi L.Morelli L.Papiris K.Greenhalf W.Izbicki J. R.Kiudelis V.Mohelníková-Duchoňová B.Bueno-de-Mesquita B.Vodička P.Brenner H.Diener M. K.Pezzilli R.Ivanauskas A.Salvia R.Szentesi A.Aoki M. N.Németh B. C.Sperti C.Jamroziak K.Chammas R.Oliverius M.Archibugi L.Ermini S.Novák J.Kupcinskas J.Strouhal O.Souček P.Cavestro G. M.Milanetto A. C.Vanella G.Neoptolemos J. P.Theodoropoulos G. E.van Laarhoven H. W. M.Mambrini A.Moz S.Kala Z.Loveček M.Basso D.Uzunoglu F. G.Hackert T.Testoni S. G. G.Hlaváč V.Andriulli A.Lucchesi M.Tavano F.Carrara S.Hegyi P.Arcidiacono P. G.Busch O. R.Lawlor R. T.Puzzono M.Boggi U.Guo F.Małecka-Panas E.Capurso G.Landi S.Talar-Wojnarowska R.Strobel O.Gao X.Vashist Y.Campa D.Canzian F. 2021 Frontiers in Oncology. 11: 771312.

Telomeric repeat-containing RNA (TERRA): Physiological functions and relevance in cancer.

Department of Molecular Biology of Cancer Kroupa M.Tomášová K.Kavec M.Skrobanek P.Buchler T.Kumar R.Vodičková L.Vodička P. 2022 Frontiers in Oncology. 12: 913314.

Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients.

Department of Molecular Biology of Cancer Kavec M.Urbanová M.Makovický P.Opattová A.Tomášová K.Kroupa M.Kostovciková K.Šišková A.Navvabi N.Schneiderová M.Vymetálková V.Vodičková L.Vodička P. 2022 International Journal of Molecular Sciences. 23(10): 5704.

Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition.

Department of Molecular Biology of Cancer Jungwirth J.Urbanová M.Boot A.Hošek P.Bendová P.Šišková A.Švec J.Kment M.Tůmová D.Summerová S.Beneš Z.Buchler T.Kohout P.Hucl T.Matěj R.Vodičková L.van Wezel T.Vodička P.Vymetálková V. 2022 Scientific Reports. 12(1): 2570.

MiR-140 leads to MRE11 downregulation and ameliorates oxaliplatin treatment and therapy response in colorectal cancer patients.

Department of Molecular Biology of Cancer Horák J.Dolníková A.Cumaogullari O.Čumová A.Navvabi N.Vodičková L.Levy M.Schneiderová M.Liška V.Andera L.Vodička P.Opattová A. 2022 Frontiers in Oncology. 12:959407.

Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6.

Department of Molecular Biology of Cancer Clay-Gilmour A.Chattopadhyay S.Hildebrandt M.A.T.Thomsen H.Weinhold N.Vodička P.Vodičková L.Hoffmann P.Nothen M.M.Jockel K.H.Schmidt B.Langer Ch.Hájek R.Hallmans G.Pettersson-Kymmer U.Ohlsson C.Spath F.Houlston R.Goldschmidt H.Manasanch E.E.Norman A.Kumar S.Rajkumar S.V.Slager S.Forsti A.Vachon C.M.Hemminki K. 2022 Blood Cancer Journal. 12(4):60

Huntingtin Co-Isolates with Small Extracellular Vesicles from Blood Plasma of TgHD and KI-HD Pig Models of Huntington's Disease and Human Blood Plasma.

Department of Molecular Biology of Cancer Ananbeh H.Novák J.Juhas S.Juhasova J.Klempir J.Doleckova K.Rysankova I.Turnovcová K.Hanus J.Hansikova H.Vodička P.Skalnikova Kupcova H. 2022 International Journal of Molecular Sciences. 23(10): 5598.

The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction.

Department of Molecular Biology of Cancer Vodička P.Andera L.Opattová A.Vodičková L. 2021 Cancer. 13(3): 479.

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.

Department of Molecular Biology of Cancer Thomas M.Sakoda L. C.Hoffmeister M.Rosenthal E. A.Lee J. K.van Duijnhoven F. J. B.Platz E. A.Wu A. H.Dampier C. H.de la Chapelle A.Wolk A.Joshi A. D.Burnett-Hartman A.Gsur A.Lindblom A.Castells A.Win A. K.Namjou B.Van Guelpen B.Tangen C. M.He Q.Li C. I.Schafmayer C.Joshu C. E.Ulrich C. M.Bishop D. T.Buchanan D. D.Schaid D.Drew D. A.Muller D. C.Duggan D.Crosslin D. R.Albanes D.Giovannucci E. L.Larson E.Qu F.Mentch F.Giles G. G.Hakonarson H.Hampel H.Stanaway I. B.Figueiredo J. C.Huyghe J. R.Minnier J.Chang-Claude J.Hampe J.Harley J. B.Visvanathan K.Curtis K. R.Offit K.Li L.Le Marchand L.Vodickova L.Gunter M. J.Jenkins M. A.Slattery M. L.Lemire M.Woods M. O.Song M.Murphy N.Lindor N. M.Dikilitas O.Pharoah P. D. P.Campbell P. T.Newcomb P. A.Milne R. L.MacInnis R. J.Castellví-Bel S.Ogino S.Berndt S. I.Bézieau S.Thibodeau S. N.Gallinger S. J.Zaidi S. H.Harrison T. A.Keku T. O.Hudson T. J.Vymetálková V.Moreno V.Martín V.Arndt V.Wei W.-Q.Chung W.Su Y.-R.Hayes R. B.White E.Vodička P.Casey G.Gruber S. B.Schoen R. E.Chan A. T.Potter J. D.Brenner H.Jarvik G. P.Corley D. A.Peters U.Hsu L. 2020 American Journal of Human Genetics. 107(3): 432-444.

Non-Coding RNAs as Biomarkers of Tumor Progression and Metastatic Spread in Epithelial Ovarian Cancer.

Department of Molecular Biology of Cancer Šeborová K.Václavíková R.Rob L.Souček P.Vodička P. 2021 Cancers. 13(8): 1839.

Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts.

Department of Molecular Biology of Cancer Sainz J.Garcia-Verdejo F.J.Martinez-Bueno M.Kumar A.Sanchez-Maldonado J.M.Diez-Villanueva A.Vodičková L.Vymetálková V.Sanchez V.M.Da Silva F.M.I.Sampaio-Marques B.Březina S.Butterbach K.ter Horst R.Hoffmeister M.Ludovico P.Jurado M.Sanchez-Rovira P.Netea M.G.Gsur A.Vodička P.Moreno V.Hemminki K.Brenner H.Chang-Claude J.Forsti A. 2021 Cancer. 13(6):1258.

Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.

Department of Molecular Biology of Cancer Pistoni L.Gentiluomo M.Lu Y.Maturana E.L.Hlaváč V.Vanella G.Darvasi E.Milanetto A.C.Oliverius M.Vashist Y.Di Leo M.Mohelniková-Duchoňová B.Talar-Wojnarowská R.Gheorghe C.Petrone M.Ch.Strobel O.Arcidiacono P.G.Vodičková L.Szentesi A.Capurso G.Gajdan L.Malleo G.Theodoropoulos G.E.Basso D.Souček P.Brenner H.Lawlor R.T.Morelli L.Ivanauskas A.Kauffmann E.F.Macauda A.Gazouli M.Archibugi L.Nentwich M.Cavestro G.M.Vodička P.Landi S.Tavano F.Sperti C.Hackert T.Kupcinskas J.Pezzilli R.Andriulli A.Pollina L.Kreivenaite E.Gioffreda D.Jamroziak K.Hegyi P.Izbicki J.R.Testoni S.G.G.Zuppardo R.A.Bozzato D.Neoptolemos J.P.Malats N.Canzian F.Campa D. 2021 Carcinogenesis. 42(8): 1037-1045.

Genetic Polymorphisms Involved in Mitochondrial Metabolism and Pancreatic Cancer Risk.

Department of Molecular Biology of Cancer Peduzzi G.Gentiluomo M.Tavano F.Arcidiacono P. G.Ermini S.Vodička P.Boggi U.Cavestro G. M.Capurso G.Morelli L.Milanetto A. C.Pezzilli R.Lawlor R. T.Carrara S.Lovecek M.Souček P.Guo F.Hackert T.Uzunoğlu F. G.Gazouli M.Párniczky A.Kupcinskas J.Bijlsma M. F.Bueno-de-Mesquita B.Vermeulen R.van Eijck C. H. J.Jamroziak K.Talar-Wojnarowska R.Greenhalf W.Gioffreda D.Petrone M. C.Landi S.Archibugi L.Puzzono M.Funel N.Sperti C.Piredda M. L.Mohelnikova-Duchonova B.Lu Y.Hlaváč V.Gao X.Schneider M.Izbicki J. R.Theodoropoulos G. E.Bunduc S.Kreivenaite E.Busch O. R.Małecka-Panas E.Costello E.Perri F.Testoni S. G. G.Vanella G.Pasquali C.Oliverius M.Brenner H.Loos M.Götz M.Georgiou K.Erőss B.Maiello E.Szentesi A.Bazzocchi F.Basso D.Neoptolemos J. P.Hegyi P.Kiudelis V.Canzian F.Campa D. 2021 Cancer Epidemiology Biomarkers & Prevention. 30 (12): 2342-2345.

Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study.

Department of Molecular Biology of Cancer Nounu A.Richmond R.C.Stewart I.D.Surendran P.Wareham N.J.Butterworth A.Weinstein S.J.Albanes D.Baron J.A.Hopper J.L.Figueiredo J.C.Newcomb P.A.Lindor N.M.Casey G.Platz E.A.Marchand L.L.Ulrich C.M.Li Ch.I.van Dujinhoven F.J.B.Gsur A.Campbell P.T.Vodička P.Vodičková L.Amitay E.Alwers E.Chang-Claude J.Sakoda L.C.Slattery M.L.Schoen R.E.Gunter M.J.Castellví-Bel S.Kim H.R.Kweon S.S.Chan A.T.Li L.Zheng W.Bishop D.T.Buchanan D.D.Giles G.G.Gruber S.B.Rennert G.Stadler Z.K.Harrison T.A.Lin Y.Keku T.O.Woods M.O.Schafmayer C.Guelpen B.V.Gallinger S.Hampel H.Berndt S.I.Pharoah P.D.P.Lindblom A.Wolk A.Wu A.H.White E.Peters U.Drew D.A.Scherer D.Bermejo J.L.Brenner H.Hoffmeister M.Williams A.C.Relton C.L. 2021 Nutrients. 13(11):4164.

A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer.

Department of Molecular Biology of Cancer Nounu A.Greenhough A.Heesom K.J.Richmond R.C.Zheng J.Weinstein S.J.Albanes D.Baron J.A.Hopper J.L.Figueiredo J.C.Newcomb P.A.Lindor N.M.Casey G.Platz E.A.Le Marchand L.Ulrich C.M.Li Ch.I.van Duijnhoven F.J.B.Gsur A.Campbell P.T.Moreno V.Vodička P.Vodičková L.Brenner H.Chang-Claude J.Hoffmeister M.Sakoda L.C.Slattery M.Schoen R.E.Gunter M.J.Castellvi-Bel S.Kim H.R.Kweon S.S.Chan A.Li L.Zheng W.Bishop D.T.Buchanan D.D.Giles G.G.Gruber S.B.Rennert G.Stadler Z.K.Harrison T.A.Lin Y.Keku T.O.Woods M.O.Schafmayer C.Van Guelpen B.Gallinger S.Hampel H.Berndt S.I.Pharoah P.D.P.Lindblom A.Wolk A.Wu A.N.H.White E.Peters U.Drew D.A.Scherer D.Bermejo J.L.Williams A.C.Relton C.L. 2021 Cancer Epidemiology Biomarkers a Prevention. 30(3): 564-575.

DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations.

Department of Molecular Biology of Cancer Niazi Y.Thomsen H.Smolková B.Vodičková L.Vodenková S.Kroupa M.Vymetálková V.Kazimírová A.Barancoková M.Volkovová K.Staruchová M.Hoffmann P.Noethen M.M.Dusinska M.Musak L.Vodička P.Hemminki K.Foersti A. 2021 Frontiers in Genetics. 12: 691947.

DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population.

Department of Molecular Biology of Cancer Niazi Y.Thomsen H.Smolková B.Vodičková L.Vodenková S.Kroupa M.Vymetálková V.Kazimírová A.Barancoková M.Volkovová K.Staruchová M.Hoffmann P.Noethen M.Dusinská M.Musak L.Vodička P.Foersti A.Hemminki K. 2021 DNA Repair. 101: 103079.

International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders.

Department of Molecular Biology of Cancer Department of Toxicology and Molecular Epidemiology Milić M.Ceppi M.Bruzzone M.Azqueta A.Brunborg G.Godschalk R.Koppen G.Langie S.Møller P.Teixeira J. P.Alija A.Anderson D.Andrade V.Andreoli C.Asllani F.Bangkoglu E. E.Barančoková M.Basaran N.Boutet-Robinet E.Buschini A.Cavallo D.Pereira C. C.Costa C.Costa S.Da Silva J.Del Bo‘ C.Srećković V. D.Djelić N.Dobrzyńska M.Duračková Z.Dvořáková M.Gajski G.Galati S.García Lima O.Giovannelli L.Goroshinskaya I. A.Grindel A.Gutzkow K. B.Hernández A.Hernández C.Holven K. B.Ibero-Baraibar I.Ottestad I.Kadioglu E.Kažimirová A.Kuznetsova E.Ladeira C.Laffon B.Lamonaca P.Lebailly P.Louro H.Cardoso T. M.Marcon F.Marcos R.Moretti M.Moretti S.Najafzadeh M.Nemeth Z.Neri M.Novotna B.Orlow I.Paduchova Z.Pastor S.Perdry H.Spremo-Potparević B.Ramadhani D.Riso P.Rohr P.Rojas E.Rössner P.Safar A.Sardas S.Silva M. J.Sirota N.Smolkova B.Staruchova M.Stetina R.Stopper H.Surikova E. I.Ulven S. M.Ursini C. L.Valdiglesias V.Valverde M.Vodička P.Volkovova K.Wagner K.-H.Živković L.Dušinská M.Collins A. R.Bonassi S. 2021 Mutation Research-Reviews in Mutation Research. 787: 108371.

Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk.

Department of Molecular Biology of Cancer Lu Y.Corradi C.Gentiluomo M.López de Maturana E.Theodoropoulos G. E.Roth S.Maiello E.Morelli L.Archibugi L.Izbicki J. R.Sarlós P.Kiudelis V.Oliverius M.Nóbrega Aoki M.Vashist Y.van Eijck C. H. J.Gazouli M.Talar-Wojnarowska R.Mambrini A.Pezzilli R.Bueno-de-Mesquita B.Hegyi P.Souček P.Neoptolemos J. P.Di Franco G.Sperti C.Kauffmann E. F.Hlaváč V.Uzunoğlu F. G.Ermini S.Małecka-Panas E.Lucchesi M.Vanella G.Dijk F.Mohelníková-Duchoňová B.Bambi F.Petrone M. C.Jamroziak K.Guo F.Kolarova K.Capretti G.Milanetto A. C.Ginocchi L.Loveček M.Puzzono M.van Laarhoven H. W. M.Carrara S.Ivanauskas A.Papiris K.Basso D.Arcidiacono P. G.Izbéki F.Chammas R.Vodička P.Hackert T.Pasquali C.Piredda M. L.Costello-Goldring E.Cavestro G. M.Szentesi A.Tavano F.Włodarczyk B.Brenner H.Kreivenaite E.Gao X.Bunduc S.Vermeulen R. C. H.Schneider M. A.Latiano A.Gioffreda D.Testoni S. G. G.Kupcinskas J.Lawlor R. T.Capurso G.Malats N.Campa D.Canzian F. 2021 Frontiers in Genetics. 12: 693933.

Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients.

Department of Molecular Biology of Cancer Department of Toxicology and Molecular Epidemiology Kroupa M.Rachakonda S.Vymetálková V.Tomášová K.Liška V.Vodenková S.Čumová A.Rössnerová A.Vodičková L.Hemminki K.Souček P.Kumar R.Vodička P. 2020 Mutagenesis. 35(6):491-497.

Genetic architectures of proximal and distal colorectal cancer are partly distinct.

Department of Molecular Biology of Cancer Huyghe J.R.Harrison T.A.Bien S.A.Hampel H.Figueiredo J.C.Schmit S.L.Conti D.V.Chen S.Qu C.Lin Y.Barfield R.Baron J.A.Cross A.J.Diergaarde B.Duggan D.Harlid S.Imaz L.Kang H.M.Levine D.M.Perduca V.Perez-Cornago A.Sakoda L.C.Schumacher F.R.Slattery M.L.Toland A.E.van Duijnhoven F.J.B.Van Guelpen B.Agudo A.Albanes D.Alonso M.H.Anderson K.Arnau-Collell C.Arndt V.Banbury B.L.Bassik M.C.Berndt S.I.Bézieau S.B.Bishop D.T.Boehm J.Boeing H.Boutron-Ruault M.-C.Brenner H.Brezina S.Buch S.Buchanan D.D.Burnett-Hartman A.Caan B.J.Campbell P.T.Carr P.R.Castells A.Castellví-Bel S.Chan A.T.Chang-Claude J.Chanock S.J.Curtis K.R.de la Chapelle A.Easton D.F.English D.R.Feskens E.J.M.Gala M.Gallinger S.J.Gauderman W.J.Giles G.G.Goodman P.J.Grady W.M.Grove J.S.Gsur A.Gunter M.J.Haile R.W.Hampe J.Hoffmeister M.Hopper J.L.Hsu W.-L.Huang W.-Y.Hudson T.J.Jenab M.Jenkins M.A.Joshi A.D.Keku T.O.Kooperberg C.Kühn T.Küry S.Le Marchand L.Lejbkowicz F.Li C.I.Li L.Lieb W.Lindblom A.Lindor N.M.Männistö S.Markowitz S.D.Milne R.L.Moreno L.Murphy N.Nassir R.Offit K.Ogino S.Panico S.Parfrey P.S.Pearlman R.Pharoah P.D.P.Phipps A.I.Platz E.A.Potter J.D.Prentice R.L.Qi L.Raskin L.Rennert G.Rennert H.S.Riboli E.Schafmayer C.Schoen R.E.Seminara D.Song M.Su Y.-R.Tangen C.M.Thibodeau S.N.Thomas D.C.Trichopoulou A.Ulrich C.M.Visvanathan K.Vodička P.Vodičková L.Vymetálková V.Weigl K.Weinstein S.J.White E.Wolk A.Woods M.O.Wu A.H.Abecasis G.R.Nickerson D.A.Scacheri P.C.Kundaje A.Casey G.Gruber S.B.Hsu L.Moreno V.Hayes R.B.Newcomb P.A.Peters U. 2021 Gut. 70(7): 1325-1334.

Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects.

Department of Molecular Biology of Cancer Guo X.Lin W.Wen W.Huyghe J.Bien S.Cai Q.Harrison T.Chen Z.Qu C.Bao J.Long J.Yuan Y.Wang F.Bai M.Abecasis G.R.Albanes D.Berndt S.I.Bézieau S.Bishop D.T.Brenner H.Buch S.Burnett-Hartman A.Campbell P.T.Castellví-Bel S.Chan A.T.Chang-Claude J.Chanock S.J.Cho S.H.Conti D.V.de la Chapelle A.Feskens E.J.M.Gallinger S.J.Giles G.G.Goodman P.J.Gsur A.Guinter M.Gunter M.J.Hampe J.Hampel H.Hayes R.B.Hoffmeister M.Kampman E.Kang H.M.Keku T.O.Kim H.R.Le Marchand L.Lee S.C.Li C.I.Li L.Lindblom A.Lindor N.Milne R.L.Moreno V.Murphy N.Newcomb P.A.Nickerson D.A.Offit K.Pearlman R.Pharoah P.D.P.Platz E.A.Potter J.D.Rennert G.Sakoda L.C.Schafmayer C.Schmit S.L.Schoen R.E.Schumacher F.R.Slattery M.L.Su Y.-R.Tangen C.M.Ulrich C.M.van Duijnhoven F.J.B.van Guelpen B.Visvanathan K.Vodička P.Vodičková L.Vymetálková V.Wang X.White E.Wolk A.Woods M.O.Casey G.Hsu L.Jenkins M.A.Gruber S.B.Peters U.Zheng W. 2021 Gastroenterology. 160(4) 1164–1178.

Lack of association of CD44-rs353630 and CHI3L2-rs684559 with pancreatic ductal adenocarcinoma survival.

Department of Molecular Biology of Cancer Gentiluomo M.Corradi Ch.Vanella G.Johansen A. Z.Strobel O.Szentesi A.Milanetto A.Hegyi P.Kupcinskas J.Tavano F.Neoptolemos J.P.Bozzato D.Hackert T.Pezzilli R.Johansen J.S.Costello E.Mohelniková-Duchonová B.van Eijck C.H.J.Talar-Wojnarowská R.Hansen C.P.Darvasi E.Chen I.Cavestro G.M.Souček P.Piredda L.Vodička P.Gazouli M.Arcidiacono P.G.Canzian F.Campa D.Capurso G. 2021 Scientific Reports. 11(1): 7570.

Polygenic and multifactorial scores for pancreatic ductal adenocarcinoma risk prediction.

Department of Molecular Biology of Cancer Galeotti A.A.Gentiluomo M.Rizzato C.Obazee O.Neoptolemos J.P.Pasquali C.Nentwich M.Cavestro G.M.Pezzilli R.Greenhalf W.Holleczek B.Schroeder C.Schöttker B.Ivanauskas A.Ginocchi L.Key T.J.Hegyi P.Archibugi L.Darvasi E.Basso D.Sperti C.Bijlsma M.F.Palmieri O.Hlaváč V.Talar-Wojnarowská R.Mohelniková-Duchoňová B.Hackert T.Vashist Y.Strouhal O.Laarhoven H.Tavano F.Loveček M.Dervenis Ch.Izbéki F.Padoan A.Małecka-Panas E.Maiello E.Vanella G.Capurso G.Izbicki J.R.Theodoropoulos G.E.Jamroziak K.Katzke V.Kaaks R.Mambrini A.Papanikolaou I.S.Szmola R.Szentesi A.Kupcinskas J.Bursi S.Costello E.Boggi U.Milanetto A.C.Landi S.Gazouli M.Vodičková L.SoučekGioffreda D.Gemignani D.Brenner H.Strobel O.Büchler M.Vodička P.Paiella S.Canzian F.Campa D. 2021 Journal of Medical Genetics. 58(6): 369-377.

Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.

Department of Molecular Biology of Cancer Čumová A.Vymetálková V.Opattová A.Boušková V.Pardini B.Kopečkov K.Kozevnikovová R.Licková K.Ambrus M.Vodičková L.Naccarati A.Souček P.Vodička P. 2021 Mutagenesis. 36(4): 269-279.

Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study.

Department of Molecular Biology of Cancer Červená K.Pardini B.Urbanová M.Vodenková S.Pazourková E.Veškrnová V.Levy M.Buchler T.Mokrejs M.Naccarati A.Vodička P.Vymetálková V. 2021 Mutagenesis. 36(5): 358-268.

Local Immune Changes in Early Stages of Inflammation and Carcinogenesis Correlate with the Collagen Scaffold Changes of the Colon Mucosa.

Department of Molecular Biology of Cancer Čaja F.Stakheev D.Chernyavskiy O.Kubinová L.Krizan J.Dvořák J.Rossmann P.Štěpánková R.Makovický P.Makovický P.Vymetálková V.Souček P.Vodička P.Vodičková L.Levý M.Vannucci L. 2021 Cancers. 13(10): 2463.

Genome-wide scan of long noncoding RNA single nucleotide polymorphisms and pancreatic cancer susceptibility.

Department of Molecular Biology of Cancer Corradi C.Gentiluomo M.Gajdan L.Cavestro G.M.Kreivenaite E.Di Franco G.Sperti C.Giaccherini M.Petrone M. Ch.Tavano F.Gioffreda D.Morelli L.Souček P.Andriulli A.Izbicki J.R.Napoli N.Malecka-Panas E.Hegyi P.Neoptolemos J.P.Landi S.Vashist Y.Pasquali C.Lu Y.Červená K.Theodoropoulos G.Moz S.Capurso G.Strobel O.Carrara S.Hackert T.Hlaváč V.Archibugi L.Oliverius M.Vanella G.Vodička P.Arcidiacono P.G.Pezzilli R.Milanetto A.C.Lawlor R.T.Ivanauskas A.Szentesi A.Kupcinskas J.Testoni S.G.G.Loveček M.Nentwich M.Gazouli M.Luchini C.Zuppardo R.A.Darvasi E.Brenner H.Gheorghe C.Jamroziak K.Canzian F.Campa D. 2021 International Journal of Cancer. 148(11): 2779-2788.

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study.

Department of Molecular Biology of Cancer Bull C.J.Bell J.A.Murphy N.Sanderson E.Smith G.D.Timpson N.J.Banbury B.L.Albanes D.Berndt S.I.Bezieau S.Bishop D. T.Brenner H.Buchanan D.D.Burnett-Hartman A.Casey G.Castellvi-Bel S.Chan A.Chang-Claude J.Cross A.J.de la Chapelle A.Figueiredo J.C.Gallinger S. J.Gapstur S.M.Giles G.G.Gruber S.B.Gsur A.Hampe J.Hampel H.Harrison T.A.Hoffmeister M.Hsu L.Huang W.Y.Huyghe J.R.Jenkins M. A.Joshu C.E.Keku T.O.Kuhn T.Kweon S.S.Le Marchand L.Li Ch.S.I.Li L.Lindblom A.Martin V.May A.M.Milne R.L.Moreno V.Newcomb P.A.Offit K.Ogino S.Phipps A.I.Platz E.A.Potter J.D.Qu C.Quiros J. R.Rennert G.Riboli E.Sakoda L.C.Schafmayer C.Schoen R.E.Slattery M.L.Tangen C.M.Tsilidis K.K.Ulrich C.M.van Duijnhoven F.J.B.van Guelpen B.Visvanathan K.Vodička P.Vodičková L.Wang H.S.White E.Wolk A.Woods M.O.Wu A.H.Campbell P.T.Zheng W.Peters U.Vincent E.E.Gunter M.J. 2020 BMC Medicine. 18(1): 396.

Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer.

Department of Molecular Biology of Cancer Bendová P.Pardini B.Susová S.Rosendorf J.Levy M.Skrobánek P.Buchler T.Král J.Liska V.Vodičková L.Landi S.Souček, P.Naccarati A.Vodička P.Vymetálková V. 2021 Carcinogenesis. 42(3): 378-394.

The dynamics of telomere length in primary and metastatic colorectal cancer lesions

Department of Molecular Biology of Cancer Kroupa M.Kubecek O.Tomášová K.Hanák P.Krupová M.Červená K.Šišková A.Rosendorf J.Hosek P.Vodičková L.Vodička P.Liška V.John S.Vymetálková V.Petera J. 2023 Sci Rep . 2023 Jun 5;13(1):9097. doi: 10.1038/s41598-023-35835-9.

MUC13-miRNA-4647 axis in colorectal cancer: Prospects to identifications of risk factors and clinical outcomes.

Department of Molecular Biology of Cancer Sojka L.Opattová A. Bartů L.Horák J.Kořenková V.Novosadová V.Krížková V.Bruha J.Liška V.Schneiderová M.Kubecek O.Vodičková L.Urbanová M.Simsa J.Vodička P.Vymetálková V. 2023 Oncology Letters. 25 (2): 72.

An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay.

Department of Molecular Biology of Cancer Vodička P.Vodenková S.Horák J.Opattová A.Tomášová K.Vymetálková V.Stetina R.Hemminki K.Vodičková L. 2023 Mutation Research – Genetic Toxicology and Environmental Mutagenesis. 885: 503564.

Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.

Department of Molecular Biology of Cancer Murphy N.Song M.Papadimitriou N.Carreras-Torres R.Langenberg C.Martin R.M.Tsilidis K.K.Barroso I.Chen J.Frayling T.Bull C.J.Vincent E.E.Cotterchio M.Gruber S.B.Pai R.K.Newcomb P.A.Perez-Cornago A.van Duijnhoven F.J.B.Van Guelpen B.Vodička P.Wolk A.Wu A.H.Peters U.Chan A.T.Gunter M. 2022 JNCI-Journal of the National Cancer Institute. 114(5): 740-752.

Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region.

Department of Molecular Biology of Cancer Jordahl K.M.Shcherbina A.Kim A.E.Su Y.R.Lin Y.Wang J.Qu C.Albanes D.Arndt V.Baurley J.W.Berndt S.I.Bien S.A.Bishop D.T.Bouras E.Brenner H.Buchanan D.D.Budiarto A.Campbell P.T.Carreras-Torres R.Casey G.Cenggoro T.W.Chan A.T.Conti D.V.Dampier C.H.Devall M.A.Diez-Obrero V.Dimou N.Drew D.A.Figueiredo J.C.Gallinger S.Giles G.G.Gruber S.B.Gsur A.Gunter M.J.Hampel H.Harlid S.Harrison T.A.Hidaka A.Hoffmeister M.Huyghe J.R.Jenkins M.A.Joshi A.D.Keku T.O.Larsson S.C.Marchand L.L.M.Lewinger J.P.Li L.Mahesworo B.Moreno V.Morrison J.L.Murphy N.Nan H.Nassir R.Newcomb P.A.Obon-Santacana M.Ogino S.Ose J.Pai R.K.Palmer J.R.Papadimitriou N.Pardamean B.Peoples A.R.Pharoah P.D.P.Platz E.A.Potter J.D.Prentice R.L.Rennert G.Ruiz-Narvaez E.A.Sakoda L.C.Scacheri P.C.Schmit S.L.Schoen R.E.Slattery M.L.Stern M.C.Tangen C.M.Thibodeau S.N.Thomas D.C.Tian Y.Tsilidis K.K.Ulrich C.M.Duijnhoven F.J.B.V.Guelpen B.V.Visvanathan K.Vodička P.White E.Wolk A.Woods M.O.Wu A.H.Zemlianskaia N.Chang-Claude J.Gauderman W.J.Hsu L.Kundaje A.Peters U. 2022 Cancer Epidemiology Biomarkers & Prevention. 31(5): 1077-1089.

A pooled analysis of molecular epidemiological studies on modulation of DNA repair by host factors.

Department of Molecular Biology of Cancer Opattová A.Langie S.A.S.Milic M.Collins A.Brevik A.Coskun E.Dusinská M.Gaivao I.Kadioglu E.Laffon B.Marcos R.Pastor S.Slyšková J.Smolková B.Szilagyi Z.Valdiglesias V.Vodička P.Volkovová K.Bonassi S.Godschalk R.W.L. 2022 Mutation Research – Genetic Toxicology and Environmental Mutagenesis. 876: 503447.

Analysis of MicroRNA Expression Changes During the Course of Therapy In Rectal Cancer Patients.

Department of Molecular Biology of Cancer Červená K.Novosadová V.Pardini B.Naccarati A.Opattová A.Horák J.Vodenková S.Buchler T.Skrobanek P.Levy M.Vodička P.Vymetálková V. 2021 Front Oncol . 2021 Sep 2:11:702258. doi: 10.3389/fonc.2021.702258. eCollection 2021.

Truncated PPM1D impairs response to genotoxic stress and promotes growth of APCmin induced tumors in mouse colon.

Department of Molecular Biology of Cancer Burocziová M.Burdová K.Vieru A.S.Kasparek P.Kleiblová P.Danielsen S.A.Zemanková P.Jeniková G.Pavel J.Tichá I.Xiao-Feng S.Janečková L.Borecká M.Schneiderová M.Schwarzová L.Vodičková L.Vodička P.Jirásková K.Liska V.Sedláček R.Kleibl Z.Ragenhild L.Kořínek V.Macurek L. 2019 Cell Death and Disease. 10: 818.

Diagnostic and prognostic impact of cell-free DNA in human cancers: Systematic review

Department of Molecular Biology of Cancer Červená K.Vodička P.Vymetálková V. 2019 Mutat Res Rev Mutat Res . 2019 Jul-Sep;781:100-129. doi: 10.1016/j.mrrev.2019.05.002. Epub 2019 May 11.

Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients

Department of Molecular Biology of Cancer Gentiluomo M.Garcia P.P.Galeotti A.A.Talar-Wojnarowska R.Tjaden C.Tavano F.Strobel O.Kupcinskas J.Neoptolemos J.Hegyi P.Costello E.Pezzilli R.Sperti C.Lawlor R.T.Capurso G.Szentesi A.Souček P.Vodička P.Loveček M.Hackert T.Cavestro G.M.Milanetto A.C.Canzian F.Campa D. 2019 Carcinogenesis. 2019 Jun 10;40(4):544-550. doi: 10.1093/carcin/bgz006.

Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study.

Department of Molecular Biology of Cancer Campa D.Matarazzi M.Greenhalf W.Bijlsma M.Saum K.U.Pasquali C.van Laarhoven H.Szentesi A.Federici F.Vodička P.Vodička P.Funel N.Pezzilli R.Bueno-de-Mesquita H. B.Vodičková L.Basso D.Obazee O.Hackert T.Souček P.Cuk K.Kaiser J.Sperti C.Loveček M.Capurso G.Mohelníková-Duchoňová B.Khaw K. T.König A.K.Kupcinskas J.Kaaks R.Bambi F.Archibugi L.Mambrini A.Cavestro G.M.Landi S.Hegyi P.Izbicki J.R.Gioffreda D.Zambon C.F.Tavano F.Talar-Wojnarowska R.Jamroziak K.Key T. J.Fave G.D.Strobel O.Jonaitis L.Andriulli A.Lawlor R.T.Pirozzi F.Katzke V.Valsuani Ch.Vashist Y.K.Brenner H.Canzian F. 2019 International Journal of Cancer. 144 (6):1275-1288.