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Institutional Seminar Series 2/2025

Metabolic tuning of mesenchymal stromal cells to improve therapeutic potential

Lecturer: Olena Rohulska, Ph.D.  / Department of Neuroregeneration

Annotatiom: Mesenchymal stromal cells (MSC) offer therapeutic promise due to their regenerative and immunomodulatory abilities. Within the seminar, we will explore how cytokine licensing, particularly with TNF-α and IFN-γ, impacts MSC paracrine activity, differentiation, and cell metabolic profile. Combining transcriptomics, metabolomics, and functional assays, we aim to provide a multi-dimensional understanding of the licensing effect on MSC functions, revealing both beneficial and detrimental effects.

The seminar will take place on 6. 2. 2025 from 2 p.m. in the Turquoise Auditorium of the IEM CAS.

We look forward to your participation.