Metabolic tuning of mesenchymal stromal cells to improve therapeutic potential
Lecturer: Olena Rohulska, Ph.D. / Department of Neuroregeneration
Annotatiom: Mesenchymal stromal cells (MSC) offer therapeutic promise due to their regenerative and immunomodulatory abilities. Within the seminar, we will explore how cytokine licensing, particularly with TNF-α and IFN-γ, impacts MSC paracrine activity, differentiation, and cell metabolic profile. Combining transcriptomics, metabolomics, and functional assays, we aim to provide a multi-dimensional understanding of the licensing effect on MSC functions, revealing both beneficial and detrimental effects.
The seminar will take place on 6. 2. 2025 from 2 p.m. in the Turquoise Auditorium of the IEM CAS.
We look forward to your participation.