Department

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Centre for Reconstructive Neuroscience

Research Centre

Head of the Department

James Fawcett

Publications

Select year

Integrated multi-omics profiling uncovers miRNA-guided regulatory networks after spinal cord injury in rats

 DepartmentDepartment of Neuroregeneration AutořiKlassen R. A.Chytilova S.Arzhanov I.Zucha D.Rohlova E.Androvic P.Abaffy P.Urdzíková-Machová L.Kubista M.Romanyuk N.Valihrach L. Published on 2025 Metadata Mol Ther Nucleic Acids . 2025 Oct 16;36(4):102746. doi: 10.1016/j.omtn.2025.102746. eCollection 2025 Dec 9.

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

 DepartmentDepartment of Neuroregeneration AutořiSmejkalová B.Ornaghi M.Štěpánková K.Schiweck J.Urdzíková-Machová L.Huelse R.Mueller S.Boehm-Sturm P.Kwok J. C. F.Fawcett J.Murk K.Eickholt B. J.Jendelová P. Published on 2025 Metadata Glia . 2025 Sep;73(9):1910-1924. doi: 10.1002/glia.70048. Epub 2025 Jun 11.

Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury

 DepartmentDepartment of Neuroregeneration Department of Auditory Neuroscience AutořiŠtěpánková K.Smejkalová B.Urdzíková-Machová L.Havelíková K.de Winter F.Suchánková S.Verhaagen J.Herynek V.Tureček R.Kwok J. C. F.Fawcett J.Jendelová P. Published on 2025 Metadata Acta Neuropathol Commun . 2025 May 2;13(1):89. doi: 10.1186/s40478-025-01995-0.

The risk of neurotechnology as an instrument of colonialism

 DepartmentDepartment of Neuroregeneration AutořiIlles J.Dudley M.Urdzíková-Machová L.Podina I.Pyrrho M. Published on 2025 Metadata Brain Commun . 2025 Apr 30;7(3):fcaf139. doi: 10.1093/braincomms/fcaf139. eCollection 2025.

Hyperactive delta isoform of PI3 kinase enables long-distance regeneration of adult rat corticospinal tract

 DepartmentDepartment of Neuroregeneration Department of Auditory Neuroscience AutořiKárová K.Polčanová Z.Knight L.Suchánková S.Nieuwenhuis B.Holota R.Herynek V.Urdzíková-Machová L.Tureček R.Kwok J. C. F.Herik J. vdVerhaagen J.Eva R.Fawcett J.Jendelová P. Published on 2025 Metadata Mol Ther. 2025 Feb 5;33(2):752-770. doi: 10.1016/j.ymthe.2024.12.040. Epub 2025 Jan 1.

Toxicity of Large and Small Surface-Engineered Upconverting Nanoparticles for In Vitro and In Vivo Bioapplications

 DepartmentDepartment of Neuroregeneration AutořiUrdzíková-Machová L.Marekova D.Vasylyshyn T. Matouš P.Patsula V.Oleksa V.Shapoval O.Vosmanská M.Liebl D.Benda A.Herynek V.Horák D.Jendelová P. Published on 2024 Metadata Int J Mol Sci . 2024 May 13;25(10):5294. doi: 10.3390/ijms25105294.

Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury

 DepartmentCentre for Reconstructive Neuroscience Department of Neuroregeneration AutořiŠtěpánková K.Chudíčková M.Šimková Z.Varea N.Kubinová Š.Urdzíková-Machová L.Jendelová P.Kwok J. C. F. Published on 2023 Metadata Sci Rep. 2023 Nov 6;13(1):19183. doi: 10.1038/s41598-023-46539-5.

Polymer-coated hexagonal upconverting nanoparticles: chemical stability and cytotoxicity

 DepartmentDepartment of Neuroregeneration AutořiPatsula V.Marekova D.Jendelová P.Nahorniak M.Shapoval O.Matouš P.Oleksa V.Konefał R.Vosmanská M.Urdzíková-Machová L.Horák D. Published on 2023 Metadata Front Chem. 2023 Jun 23:11:1207984. doi: 10.3389/fchem.2023.1207984. eCollection 2023.

Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response. Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response.

DepartmentDepartment of Neuroregeneration AutořiVargová L.Urdzíková-Machová L.Kárová K.Smejkalová B.Sursal T.Cimermanová V.Turnovcová K.Gandhi Ch.D.Jhanwar-Uniyal M.Jendelová P. Published on 2021 Metadata Biomedicines. 9(6): 593.

Planet of the AAVs: The Spinal Cord Injury Episode.

 DepartmentDepartment of Neuroregeneration AutořiŠtěpánková K.Jendelová P.Urdzíková-Machová L. Published on 2021 Metadata Biomedicines. 9(6): 613.

4-Methylumbeliferone Treatment at a Dose of 1.2 g/kg/Day Is Safe for Long-Term Usage in Rats.

 DepartmentDepartment of Neuroregeneration Centre for Reconstructive Neuroscience AutořiŠtěpánková K.Marekova D.Kubášová K.Sedláček R.Turnovcová K.Vacková I.Kubinová Š.Makovický P.Petrovičová M.Kwok J. C. F.Jendelová P.Urdzíková-Machová L. Published on 2023 Metadata International Journal of Molecular Sciences. 24 (4): 3799.

The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury.

 DepartmentDepartment of Neuroregeneration AutořiUrdzíková-Machová L.Cimermanová V.Kárová K.Dominguez J.Štěpánková K.Petrovicová M.Havelíková K.Gandhi Ch.D.Jhanwar-Uniyal M.Jendelová P. Published on 2023 Metadata Antioxidants. 12(2): 363.

Chemical and Colloidal Stability of Polymer-Coated NaYF4:Yb,Er Nanoparticles in Aqueous Media and Viability of Cells: The Effect of a Protective Coating.

 DepartmentDepartment of Neuroregeneration AutořiNahorniak M.Patsula V.Marekova D.Matous P.Shapoval O.Oleksa V.Vosmanská M.Urdzíková-Machová L.Jendelová P.Herynek V.Horák D. Published on 2023 Metadata International Journal of Molecular Sciences. 24(3): 2724.

Chemical and Colloidal Stability of Polymer-Coated NaYF4:Yb,Er Nanoparticles in Aqueous Media and Viability of Cells: The Effect of a Protective Coating

 DepartmentDepartment of Neuroregeneration AutořiNahorniak M.Patsula V.Marekova D.Matouš P.Shapoval O.Oleksa V.Vosmanská M.Urdzíková-Machová L.Jendelová P.Herynek V.Horák D. Published on 2023 Metadata Int J Mol Sci. 2023 Feb 1;24(3):2724. doi: 10.3390/ijms24032724.

New Model of Ventral Spinal Cord Lesion Induced by Balloon Compression in Rats

 DepartmentDepartment of Neuroregeneration Centre for Reconstructive Neuroscience AutořiKrůpa P.Štěpánková K.Kwok J. C. F.Fawcett J.Cimermanová V.Jendelová P.Urdzíková-Machová L. Published on 2020 Metadata Biomedicines . 2020 Nov 5;8(11):477. doi: 10.3390/biomedicines8110477.

Two-tailed RT-qPCR panel for quality control of circulating microRNA studies.

 DepartmentDepartment of Neuroregeneration AutořiAndrovic P.Romanyuk N.Urdzíková-Machová L.Rohlová E.Kubista M.Valihrach L. Published on 2019 Metadata Scientific Reports. 9: 4255.