Nanofibers and 3D bioprinting: A new era of wound treatment and tissue regeneration?

We would like to introduce the project “Innovative use of nanofibers and 3D bioprinting for regenerative medicine” (BIOM). The BIOM project focuses on the development of innovative biomaterials that will advance treatment options for damaged tendons and serious skin tissue injuries. In collaboration with Nanoprogress, z. s. (open in a new window) we develop special biodegradable and biocompatible materials in the form of nanofibrous structures and composite scaffolds created by 3D bioprinting. These materials, enriched with endogenous substances from human stem cells, allow more effective regeneration due to the gradual release of growth factors directly in the injury site.

How will the project help in practice? For tendon treatment, we develop bioactive covers that release biologically active molecules during surgery, promoting regeneration and preventing the formation of unwanted adhesions. For skin injuries, these covers will function to support the treatment of acute and chronic wounds.

A team of scientists from the Department of Tissue Engineering, led by the principal investigator, Lucie Wolfová, are working intensively on the development. The project is funded by the Operational Program Technologies and Application for Competitiveness (OP TAK). The programme is managed by the Ministry of Industry and Trade of the Czech Republic and is aimed at supporting innovation, digitalization, research and development in Czech companies. The OP TAK programme is financed from European funds, and its aim is to increase the competitiveness of the Czech industry and enterprises through modern technologies and by strengthening sustainable economic growth.