The Institute of Experimental Medicine of the CAS (IEM CAS) is looking for a suitable candidate for the position of Postdoctoral Researcher for the Department of Genome Biology.
Background
We investigate the mechanisms underpinning DNA damage and cancerogenesis, with a focus on:
- Replication Stress & Genome Instability: How oxidative stress in cancer cells leads to the formation of genotoxic R-loops and conflicts between transcription and replication complexes (TRCs).
- The omlecular mechanisms of prevention, signaling, and resolution of replication stress associated with TRCs.
- Exploiting Stress Tolerance: Studying replication stress tolerance pathways to find ways to increase cancer therapy effectiveness.
We offer
- The position is funded by a prestigious 5-year Junior Star Grant from the Czech Science Foundation.
- A full-time, fixed-term employment contract for 2 years, with possible extension.
- Attractive salary, employment benefits, and 5 weeks of vacation per year + 5 sick days.
- A collaborative scientific environment supported by state-of-the-art facilities.
- Opportunities for training and specialised courses to expand a skillset.
- Support to pursue independent funding.
Our requirements
- A PhD in molecular biology, genetics, biochemistry, or a related field.
- Proactive drive, collaborative spirit, a problem-solving mindset.
- Willingness to contribute to the foundational setup of the lab.
- Proficient in both written and spoken English.
Not required but beneficial
- Expertise in the field of DNA repair, replication, or transcription of DNA.
- Experience with advanced technologies, including light microscopy, CRISPR, omics approaches (Chip-seq, proteomics), or bioinformatics.
How to apply
Please send the following to the contact below.
- Cover letter: your motivation to apply for this position and a description of your research interests.
- CV: Highlight your skills, experience, and scientific achievements.
- References: Provide contact details for two referees.
- Application deadline: Extended until March 31, 2026
The IEM CAS reserves the right to invite only selected candidates for a personal or online interview and the right not to select any of the candidates.
